Biologics in Pediatric Rheumatology: Quo Vadis?

被引：12

作者：

Sterba, Yonit ^{[1
]}

Ilowite, Norman ^{[1
]}

机构：

[1] Childrens Hosp Montefiore, Div Pediat Rheumatol, 3415 Bainbridge Ave, Bronx, NY 10467 USA

来源：

CURRENT RHEUMATOLOGY REPORTS | 2016年 / 18卷 / 07期

关键词：

TNF inhibitors; IL-1; inhibitors; IL-6; Abatacept; Rituximab; Tofacitinib; Juvenile idiopathic arthritis (JIA); JUVENILE IDIOPATHIC ARTHRITIS; ACTIVE PSORIATIC-ARTHRITIS; SYSTEMIC-LUPUS-ERYTHEMATOSUS; PLACEBO-CONTROLLED TRIAL; DOUBLE-BLIND; WITHDRAWAL TRIAL; EFFICACY; SAFETY; METHOTREXATE; MULTICENTER;

D O I：

10.1007/s11926-016-0593-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The past two decades have brought immense satisfaction to pediatric rheumatologists and families of children with rheumatologic diseases. We have been able to better classify, recognize, and diagnose rheumatologic diseases, but most importantly, the discovery of biologic therapies and their efficacy and relative safety in treating multiple rheumatologic conditions, improving quality of life for the patients we care for. We will review the advances of the past two decades and discuss potential areas for new discoveries.

引用

页数：6

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