Immunisation and multi-dose vials

被引：10

作者：

Gosbell, Iain B. ^{[1
,2
]}

Gottlieb, Thomas ^{[3
,4
]}

Kesson, Alison M. ^{[5
,6
]}

Post, Jeffrey J. ^{[7
,8
,9
]}

Dwyer, Dominic E. ^{[10
,11
]}

机构：

[1] Univ Western Sydney, Sch Med, Microbiol & Infect Dis Unit, Sydney, NSW, Australia

[2] Sydney SW Pathol Serv Liverpool, Dept Microbiol & Infect Dis, Sydney, NSW, Australia

[3] Concord Repatriat Gen Hosp, Sydney, NSW, Australia

[4] Univ Sydney, Concord Clin Sch, Sydney, NSW 2006, Australia

[5] Childrens Hosp, Dept Infect Dis & Microbiol, Westmead, NSW, Australia

[6] Univ Sydney, Sydney Med Sch, Discipline Paediat & Child Hlth, Sydney, NSW 2006, Australia

[7] Prince Wales Hosp, Dept Infect Dis, Sydney, NSW, Australia

[8] Univ New S Wales, Sch Med Sci, Sydney, NSW, Australia

[9] Univ New S Wales, Prince Wales Clin Sch, Sydney, NSW, Australia

[10] Westmead Hosp, Inst Clin Pathol & Med Res, Ctr Infect Dis & Microbiol Lab Serv, Westmead, NSW, Australia

[11] Univ Sydney, Ctr Infect Dis & Microbiol, Western Clin Sch, Sydney, NSW 2006, Australia

来源：

VACCINE | 2010年 / 28卷 / 40期

关键词：

Influenza; Vaccine; Multi-dose Vials; Safety; Healthcare-associated infection; HEPATITIS-C VIRUS; TOXOID-PERTUSSIS VACCINATION; BLOOD-STREAM INFECTIONS; NOSOCOMIAL TRANSMISSION; HEMODIALYSIS UNIT; INFLUENZA VACCINE; HEALTH-CARE; OUTBREAK; ABSCESSES; DIPHTHERIA;

D O I：

10.1016/j.vaccine.2010.07.052

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The current novel H1N1 09 influenza virus pandemic has resulted in 37,722 diagnoses, 4992 hospitalisations, and 191 deaths in Australia as of 11 June 2010. A mass immunisation campaign has commenced using a multi-dose vial formulation to assist rapid deployment. However, in the past multi-dose vials have been associated with transmission of infective agents. Having the vaccine in single-dose vials with a lesser risk of transmission of infection but increased delay in implementation and increased cost needs to be weighed against the imperative to vaccinate the population against pandemic H1N1 09 influenza virus. This article reviews the infectious risks associated with multi-dose vials. Crown Copyright (c) 2010 Published by Elsevier Ltd. All rights reserved.

引用

页码：6556 / 6561

页数：6

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