Individualized intravenous thrombolytic strategy for acute ischemic stroke with large vessel occlusion on the era of mechanical thrombectomy: cases report

被引：1
作者：
Xing, Pengfei [1 ]
Shen, Hongjian [1 ]
Li, Zifu [1 ]
Yang, Pengfei [1 ]
Zhang, Yongwei [1 ]
Liu, Jianmin [1 ]
机构：
[1] Second Mil Med Univ, Changhai Hosp, Dept Cerebrovasc Dis Ctr, 168 Changhai Rd, Shanghai 200433, Peoples R China
来源：
NEUROLOGICAL SCIENCES | 2020年 / 41卷 / 03期
关键词：
Intravenous thrombolysis; Mechanical thrombectomy; Ischemic stroke; TISSUE-PLASMINOGEN ACTIVATOR; STANDARD-DOSE ALTEPLASE; THERAPY; TRIAL; OUTCOMES; ONSET;
D O I：
10.1007/s10072-019-04098-6
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Intravenous thrombolysis for acute ischemic stroke within 4.5 h after the onset of symptoms has become a standard therapy that is recommended by many trials and clinical guidelines. As on the era of mechanical thrombectomy for acute ischemic stroke with large vessel occlusions, whether intravenous thrombolysis (IVT) is still necessary, and how to choose the optimal dose are still controversy. Here, we reported two cases of acute ischemic stroke with large vessel occlusions that both achieved complete recanalization after IVT. Then, IVT was terminated in advance, and dynamic surveillance by DSA was performed to achieve individual treatment. However, both of the cases presented with hemorrhagic transformation. We analyzed the probable reasons and put forward thoughts from ourselves.
引用
收藏
页码：605 / 610
页数：6
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