Remote Supramolecular Control of Catalyst Selectivity in the Hydroformylation of Alkenes

被引：116

作者：

Dydio, Pawel ^{[1
]}

Dzik, Wojciech I. ^{[1
]}

Lutz, Martin ^{[2
]}

de Bruin, Bas ^{[1
]}

Reek, Joost N. H. ^{[1
]}

机构：

[1] Univ Amsterdam, Vant Hoff Inst Mol Sci, NL-1098 XH Amsterdam, Netherlands

[2] Univ Utrecht, Bijvoet Ctr Biomol Res, NL-3508 TC Utrecht, Netherlands

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 02期

关键词：

hydroformylation; hydrogen bonds; molecular recognition; P ligands; supramolecular catalysis; BIDENTATE LIGANDS; HIGH-THROUGHPUT; HYDROXYLATION; LIBRARIES;

D O I：

10.1002/anie.201005173

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the pocket: The supramolecular interactions between a Rh phosphine catalyst equipped with an anion-binding pocket and alkenes that contain anionic functionalities (see picture) provide an excellent design concept to achieve remote control of the regioselectivity in hydroformylation reactions. The 4-pentenoate and 3-butenylphosphonate, which fit tightly between the Rh center and the pocket, were hydroformylated with unprecedented selectivity. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：396 / 400

页数：5

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