Fractal Analysis of Neovascularization due to Diabetic Retinopathy in Retinal Fundus Images

被引:0
作者
Mudigonda, Sathvika [1 ]
Oloumi, Faraz [1 ]
Katta, Kalyana M. [1 ]
Rangayyan, Rangaraj M. [1 ]
机构
[1] Univ Calgary, Schulich Sch Engn, Dept Elect & Comp Engn, Calgary, AB T2N 1N4, Canada
来源
2015 E-HEALTH AND BIOENGINEERING CONFERENCE (EHB) | 2015年
关键词
Box-counting Measure; Diabetic Retinopathy; Fractal Dimension; Neovascularization; Retinal Fundus Images; DIAGNOSIS; GEOMETRY; VESSELS;
D O I
暂无
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
This study focuses on detecting and classifying neovascularization caused by proliferative diabetic retinopathy (PDR) in retinal fundus images. Image processing methods were applied to detect retinal vessels. A fractal analysis approach based on the box-counting method was used to quantify vascular patterns in normal and abnormal cases showing neovascularization near the optic disk (NVD). Ten images including five normal cases and five neovascularization cases were analyzed. The mean fractal dimension obtained for the NVD cases was 1.66 compared to the mean value of 1.52 for the normal cases. The statistical significance of the difference was high, with a p-value of 0.0088. The results show promise for use in detecting neovascularization in retinal images caused by PDR.
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页数:4
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共 34 条
[1]  
Agurto C, 2012, IEEE ENG MED BIO, P4946, DOI 10.1109/EMBC.2012.6347102
[2]  
Akram MU, 2012, LECT NOTES COMPUT SC, V7325, P372, DOI 10.1007/978-3-642-31298-4_44
[3]  
[Anonymous], BIOMEDICAL IMAGE ANA
[4]  
[Anonymous], PARSONS DIS EYE
[5]  
[Anonymous], ANN REV BIOMEDICAL E
[6]   Fractal analysis of region-based vascular change in the normal and non-proliferative diabetic retina [J].
Avakian, A ;
Kalina, RE ;
Sage, EH ;
Rambhia, AH ;
Elliott, KE ;
Chuang, EL ;
Clark, JI ;
Hwang, JN ;
Parsons-Wingerter, P .
CURRENT EYE RESEARCH, 2002, 24 (04) :274-280
[7]  
Cabral T.M., 2012, Fractal Analysis of Breast Masses in Mammograms
[8]   Quantitative Assessment of Early Diabetic Retinopathy Using Fractal Analysis [J].
Cheung, Ning ;
Donaghue, Kim C. ;
Liew, Gerald ;
Rogers, Sophie L. ;
Wang, Jie Jin ;
Lim, Shueh-Wen ;
Jenkins, Alicia J. ;
Hsu, Wynne ;
Lee, Mong Li ;
Wong, Tien Y. .
DIABETES CARE, 2009, 32 (01) :106-110
[9]   CHARACTERIZATION OF THE NEOVASCULARIZATION PROCESS IN DIABETIC-RETINOPATHY BY MEANS OF FRACTAL GEOMETRY - DIAGNOSTIC IMPLICATIONS [J].
DAXER, A .
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 1993, 231 (12) :681-686
[10]   THE FRACTAL GEOMETRY OF PROLIFERATIVE DIABETIC-RETINOPATHY - IMPLICATIONS FOR THE DIAGNOSIS AND THE PROCESS OF RETINAL VASCULOGENESIS [J].
DAXER, A .
CURRENT EYE RESEARCH, 1993, 12 (12) :1103-1109