Stress-modulated collagen fiber remodeling in a human carotid bifurcation

被引：49

作者：

Hariton, I.

debotton, G. ^{[1
]}

Gasser, T. C.

Holzapfel, G. A.

机构：

[1] Ben Gurion Univ Negev, Dept Mech Engn, Pearlstone Ctr Aeronaut Studies, IL-84105 Beer Sheva, Israel

[2] Royal Inst Technol KTH, Dept Solid Mech, S-10044 Stockholm, Sweden

[3] Graz Univ Technol, Computat Biomech, A-8010 Graz, Austria

来源：

JOURNAL OF THEORETICAL BIOLOGY | 2007年 / 248卷 / 03期

关键词：

soft tissues; carotid artery bifurcation; remodeling; hyperelasticity; FE analysis;

D O I：

10.1016/j.jtbi.2007.05.037

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

This work concerns with the implementation of a new stress-driven remodeling model for simulating the overall structure and mechanical behavior of a human carotid bifurcation. By means of an iterative finite element based procedure collagen fiber direction and maximal principal stresses are computed. We find that the predicted fibers' architecture at the cylindrical branches and at the apex of the bifurcation correlates well with histological observations. Some insights about the mechanical response of the sinus bulb and the bifurcation apex are revealed and discussed. The results are compared with other, isotropic and orthotropic, models available in the literature. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：460 / 470

页数：11

共 46 条

[31] On the overall behavior, microstructure evolution, and macroscopic stability in reinforced rubbers at large deformations:: II -: Application to cylindrical fibers [J].

Lopez-Pamies, O ;

Castañeda, PP .

JOURNAL OF THE MECHANICS AND PHYSICS OF SOLIDS, 2006, 54 (04) :831-863

[32] MECHANICAL AND DIMENSIONAL ADAPTATION OF RAT AORTA TO HYPERTENSION [J].

MATSUMOTO, T ;

HAYASHI, K .

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 1994, 116 (03) :278-283

[33] Modelling of anisotropic growth in biological tissues - A new approach and computational aspects [J].

Menzel, A .

BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2005, 3 (03) :147-171

[34]

Rachev A., 2003, CISM COURSE LECT BIO, P100

[35]

Rhodin J.A.G., 1980, Handbook of Physiology, The Cardiovascular System, V2, P1, DOI DOI 10.1002/CPHY.CP020201

[36] Collagen biomechanics in cerebral arteries and bifurcations assessed by polarizing microscopy [J].

Rowe, AJ ;

Finlay, HM ;

Canham, PB .

JOURNAL OF VASCULAR RESEARCH, 2003, 40 (04) :406-415

[37] PRESSURE-INDUCED MECHANICAL-STRESS IN THE CAROTID-ARTERY BIFURCATION - A POSSIBLE CORRELATION TO ATHEROSCLEROSIS [J].

SALZAR, RS ;

THUBRIKAR, MJ ;

EPPINK, RT .

JOURNAL OF BIOMECHANICS, 1995, 28 (11) :1333-1340

[38] CONNECTIVE-TISSUE MORPHOGENESIS BY FIBROBLAST TRACTION .1. TISSUE-CULTURE OBSERVATIONS [J].

STOPAK, D ;

HARRIS, AK .

DEVELOPMENTAL BIOLOGY, 1982, 90 (02) :383-398

[39]

Taber L.A., 1995, APPL MECH REV, V48, P487, DOI DOI 10.1115/1.3005109

[40] Stress-modulated growth, residual stress, and vascular heterogeneity [J].

Taber, LA ;

Humphrey, JD .

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 2001, 123 (06) :528-535

← 1 2 3 4 5 →