Exfoliated MXene as a mediator for efficient laser desorption/ionization mass spectrometry analysis of various analytes

被引：18
作者：
Chae, Ari [1 ,2 ]
Jang, Hongje [3 ]
Koh, Dong-Yeun [2 ]
Yang, Cheol-Min [1 ]
Kim, Young-Kwan [4 ]
机构：
[1] Korea Inst Sci & Technol, Inst Adv Composite Mat, 92 Chudong Ro, Jeonbuk 55324, South Korea
[2] Korea Adv Inst Sci & Technol, Dept Chem & Biomol Engn, Daejeon 34141, South Korea
[3] Kwangwoon Univ, Dept Chem, 20 Gwangwoon Ro, Seoul 01897, South Korea
[4] Dongguk Univ Seoul, Dept Chem, 30 Pildong Ro, Seoul 04620, South Korea
来源：
TALANTA | 2020年 / 209卷
基金：
新加坡国家研究基金会;
关键词：
MXene; Exfoliation; Metabolite; Laser desorption ionization; Mass spectrometry; SMALL MOLECULES; GRAPHENE OXIDE; MATRIX; DESORPTION; NANOSHEETS; OXIDATION; CARBON;
D O I：
10.1016/j.talanta.2019.120531
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The exfoliated MXene (e-MXene) is systematically investigated as a mediator for laser desorption/ionization time-of-flight mass spectrometry (LDI-MS) analysis. Whereas un-exfoliated MXene has no activity for LDI-MS analysis, the e-MXene presents a high resolution, salt-tolerance and efficiency for LDI-MS analysis of various small molecules regardless of their polarity, aromaticity and molecular weight owing to its physicochemical properties such as high laser energy absorption, electrical conductivity and photothermal conversion. Based on our findings, it is clearly confirmed that e-MXene is a promising material for the development of an efficient platform for LDI-MS analysis of small molecules.
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页数：7
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