Controlled size manipulation of free gold nanoparticles by laser irradiation and their facile bioconjugation

被引：128

作者：

Amendola, Vincenzo ^{[1
]}

Meneghetti, Moreno ^{[1
]}

机构：

[1] Univ Padua, Dept Chem Sci, Padua, Italy

来源：

JOURNAL OF MATERIALS CHEMISTRY | 2007年 / 17卷 / 44期

关键词：

D O I：

10.1039/b709621f

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The average size of gold nanoparticles (AuNP), obtained by laser ablation in solution, is reduced to a few nanometers or increased to tens of nanometers using laser treatments with different strategies. The techniques do not require any stabilizing molecules and the AuNP surface is free from strongly linked ligands. This allowed one-step, immediate and very efficient functionalization of AuNP with commonly used proteins like bovine serum albumin (BSA), which can be detected, using small nanoparticles, down to 3 picomoles and with a 1 : 10 concentration ratio of BSA : AuNP.

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页码：4705 / 4710

页数：6

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