The Person's Care Requires a Sex and Gender Approach

被引:16
作者
Campesi, Ilaria [1 ,2 ]
Montella, Andrea [2 ]
Seghieri, Giuseppe [3 ]
Franconi, Flavia [1 ]
机构
[1] Natl Inst Biostruct & Biosyst, Lab Sex Gender Med, I-07100 Sassari, Italy
[2] Univ Sassari, Dept Biomed Sci, I-07100 Sassari, Italy
[3] Reg Hlth Agcy Tuscany, Dept Epidemiol, I-50124 Florence, Italy
关键词
sex-gender; social aspects; interdisciplinary; caregiver; doctors' prescribing patterns; ADVERSE DRUG-REACTIONS; TO-RENIN RATIO; HEART-FAILURE; PHARMACOLOGICAL RESPONSE; SOCIAL DETERMINANTS; FAMILY CAREGIVERS; PHYSICIAN GENDER; CLINICAL-TRIALS; HEALTH; STRESS;
D O I
10.3390/jcm10204770
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
There is an urgent need to optimize pharmacology therapy with a consideration of high interindividual variability and economic costs. A sex-gender approach (which considers men, women, and people of diverse gender identities) and the assessment of differences in sex and gender promote global health, avoiding systematic errors that generate results with low validity. Care for people should consider the single individual and his or her past and present life experiences, as well as his or her relationship with care providers. Therefore, intersectoral and interdisciplinary studies are urgently required. It is desirable to create teams made up of men and women to meet the needs of both. Finally, it is also necessary to build an alliance among regulatory and ethic authorities, statistics, informatics, the healthcare system and providers, researchers, the pharmaceutical and diagnostic industries, decision makers, and patients to overcome the gender gap in medicine and to take real care of a person in an appropriate manner.
引用
收藏
页数:19
相关论文
共 208 条
[1]   Opposite-sex and same-sex twin studies of physiological, cognitive and behavioral traits [J].
Ahrenfeldt, Linda Juel ;
Christensen, Kaare ;
Segal, Nancy L. ;
Hur, Yoon-Mi .
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2020, 108 :322-340
[2]   Novel piperidine derivatives: Inhibitory properties towards cytochrome P450 isoforms, and cytoprotective and cytotoxic characteristics [J].
Alexidis, AN ;
Commandeur, JNM ;
Rekka, EA ;
Groot, E ;
Kourounakis, PN ;
Vermeulen, NPE .
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 1996, 1 (01) :81-88
[3]  
American Psychological Association, 2017, AM PSYCH ASS STRESS
[4]   Gender differences in the impact of poverty on health: disparities in risk of diabetes-related amputation [J].
Amin, L. ;
Shah, B. R. ;
Bierman, A. S. ;
Lipscombe, L. L. ;
Wu, C. F. ;
Feig, D. S. ;
Booth, G. L. .
DIABETIC MEDICINE, 2014, 31 (11) :1410-1417
[5]   Sex and racial differences in pharmacological response: Where is the evidence? Pharmacogenetics, pharmacokinetics, and pharmacodynamics [J].
Anderson, GD .
JOURNAL OF WOMENS HEALTH, 2005, 14 (01) :19-29
[6]  
[Anonymous], 2018, SEX GEND
[7]  
[Anonymous], 2018, Gender
[8]  
[Anonymous], 2013, Health 2020, A European policy framework and strategy for the 21st century
[9]  
[Anonymous], 2015, Consideration of sex as a biological variable in NIH-funded research (NOT-OD-15-102)
[10]  
[Anonymous], OFFICE WOMEN HLTH