Placental metastasis of maternal melanoma

被引:51
作者
Altman, JF [1 ]
Lowe, L [1 ]
Redman, B [1 ]
Esper, P [1 ]
Schwartz, JL [1 ]
Johnson, TM [1 ]
Haefner, HK [1 ]
机构
[1] Univ Michigan, Dept Dermatol, Taubman Ctr 1910, Ann Arbor, MI 48109 USA
关键词
D O I
10.1016/S0190-9622(03)00124-5
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Metastasis of maternal malignant tumor to the products of conception is a rare event. Melanoma is the most common maternal malignant tumor to metastasize to the placenta and the fetus. We report the case of a 28-year-old woman with melanoma during pregnancy. At parturition, histologic evaluation of the placenta revealed metastatic melanoma, and Multiple organ metastasis developed. The infant was free of disease. Metastasis to products of conception portends a poor prognosis for the mother. To our knowledge, this report is the first of a patient with melanoma metastasis to the placenta to survive more than 7 months after parturition. As caretakers of patients with melanoma, dermatologists are in a position to coordinate and direct the care and follow-up treatment of affected patients.
引用
收藏
页码:1150 / 1154
页数:5
相关论文
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