Gastrointestinal dysfunction in Parkinson's disease

被引:190
作者
Pfeiffer, Ronald F. [1 ]
机构
[1] Univ Tennessee, Hlth Sci Ctr, Dept Neurol, Memphis, TN 38163 USA
关键词
Gastrointestinal dysfunction; Dysphagia; Gastroparesis; Constipation; Anorectal dysfunction; Parkinson's disease; MULTIPLE SYSTEM ATROPHY; ENTERIC NERVOUS-SYSTEM; COLONIC TRANSIT-TIME; BOTULINUM TOXIN; RESPONSE FLUCTUATIONS; ANORECTAL FUNCTION; LEWY BODIES; SWALLOWING DISORDERS; ORAL-HEALTH; CRICOPHARYNGEAL DYSFUNCTION;
D O I
10.1016/j.parkreldis.2010.08.003
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
In recent years, an increasingly detailed picture of gastrointestinal dysfunction in the setting of Parkinson's disease has emerged. Abnormalities of function may occur at virtually all levels of the gastrointestinal tract. Weight loss, dental deterioration, salivary excess, dysphagia, gastroparesis, decreased bowel movement frequency, and anorectal dysfunction all may occur. The pathophysiologic basis for this dysfunction entails both central and enteric nervous system involvement. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:10 / 15
页数:6
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