The Challenge of Hemorrhagic Shock Management During Low-Molecular-Weight Heparin Treatment

被引：0
|
作者：
Morotti, Alessandro [1 ]
Branca, Enrica [1 ]
Guerrasio, Angelo [1 ]
机构：
[1] Univ Turin, Dept Clin & Biol Sci, Reg Gonzole 10, I-10043 Orbassano, Italy
来源：
JOURNAL OF BLOOD MEDICINE | 2020年 / 11卷
关键词：
LMWH bleeding; LMWH reversal; FVIIa; protamine; mantle lymphoma; REVERSAL;
D O I：
10.2147/JBM.S232109
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The reversal of low-molecular-weight heparin (LMWH) and the management of bleeding patients on LMWH remain highly challenging. Even if LMWH is very extensively administered in the prophylaxis and treatment of venous thrombosis, specific antidotes are lacking, and reversal strategies have very weak grade of evidences on clinical effectiveness. We here describe a reversal strategy with protamine and FVIIa in a patient presenting with hemorrhagic shock and cardiocirculatory arrest.
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页码：103 / 105
页数：3
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