SEVERE GENITAL ULCERATION IN AN ACUTE EPSTEIN-BARR VIRUS INFECTION

被引：6
作者：
Al-Rawahi, Ghada N. [1 ]
Dobson, Simon R. [2 ]
Scheifele, David W. [2 ]
Rassekh, S. Rod [3 ]
Murphy, James J. [4 ]
机构：
[1] Childrens & Womens Hlth Ctr British Columbia, Dept Pathol & Lab Med, Vancouver, BC, Canada
[2] Childrens & Womens Hlth Ctr British Columbia, Div Infect Dis, Vancouver, BC, Canada
[3] Childrens & Womens Hlth Ctr British Columbia, Dept Pediat, Vancouver, BC, Canada
[4] Childrens & Womens Hlth Ctr British Columbia, Dept Gen Surg, Vancouver, BC, Canada
来源：
PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2011年 / 30卷 / 02期
关键词：
Epstein-Barr virus (EBV); genital ulceration; ULCERS; MONONUCLEOSIS;
D O I：
10.1097/INF.0b013e3181f41b2e
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Genital ulceration is a rare manifestation of infectious mononucleosis caused by Epstein-Barr virus (EBV). We report a girl with severe genital ulceration and tissue necrosis during primary EBV infection that required surgical debridement. The excised genital tissue was EBV polymerase chain reaction-positive whereas in situ hybridization was negative. This suggests that the ulceration was likely because of the inflammatory response to the virus and not because of the intense viral infection of the genitalia.
引用
收藏
页码：176 / 178
页数：3
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