Diet induced insulin resistance is paradoxically prevented in PGC1α knockout mice but not altered in transgenic mice with muscle specific overexpression of PGC1α

被引：0
|
作者：
Choi, CS
Reznick, RM
Kulkarni, A
Kim, S
Kim, JK
Lin, JD
Spiegel-Man, BM
Shulman, GI
机构：
来源：
DIABETES | 2005年 / 54卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：A382 / A383
页数：2
相关论文
共 50 条
  • [21] Fatty liver is associated with impaired activity of PPARγ-coactivator 1α (PGC1α) and mitochondrial biogenesis in mice
    Aharoni-Simon, Michal
    Hann-Obercyger, Michal
    Pen, Svetlana
    Madar, Zecharia
    Tirosh, Oren
    LABORATORY INVESTIGATION, 2011, 91 (07) : 1018 - 1028
  • [22] Exendin-4 alleviates diabetic cardiomyopathy in mice by regulating Sirt1/PGC1α
    Guan, M.
    Cai, Y.
    Fang, S.
    Xu, L.
    Zhang, Y.
    Wang, L.
    DIABETOLOGIA, 2018, 61 : S531 - S531
  • [23] An Evolutionarily Conserved uORF Regulates PGC1α and Oxidative Metabolism in Mice, Flies, and Bluefin Tuna
    Dumesic, Phillip A.
    Egan, Daniel F.
    Gut, Philipp
    Tran, Mei T.
    Parisi, Alice
    Chatterjee, Nirmalya
    Jedrychowski, Mark
    Paschini, Margherita
    Kazak, Lawrence
    Wilensky, Sarah E.
    Dou, Florence
    Bogoslavski, Dina
    Cartier, Jeffrey A.
    Perrimon, Norbert
    Kajimura, Shingo
    Parikh, Samir M.
    Spiegelman, Bruce M.
    CELL METABOLISM, 2019, 30 (01) : 190 - +
  • [24] PGC1 expression alters lipid metabolism and partitioning in skeletal muscle cells: Potential links to insulin resistance susceptibility
    Espinoza, DO
    Patti, ME
    DIABETES, 2005, 54 : A360 - A360
  • [25] Myostatin Knockout Affects Mitochondrial Function by Inhibiting the AMPK/SIRT1/PGC1α Pathway in Skeletal Muscle
    Gu, Mingjuan
    Wei, Zhuying
    Wang, Xueqiao
    Gao, Yang
    Wang, Dong
    Liu, Xuefei
    Bai, Chunling
    Su, Guanghua
    Yang, Lei
    Li, Guangpeng
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (22)
  • [26] Activation of Pgc1α by EET Stimulates Insulin Sensitivity, Normalizes Blood Pressure and Increases Mitochondrial Oxphos in Obese Mice
    Singh, Shailendra P.
    Waldman, Maayan
    Schragenheim, Joseph
    Bellner, Lars
    Cao, Jian
    Arad, Michael
    Hochhauser, Edith
    Abraham, Nader
    HYPERTENSION, 2016, 68
  • [27] Skeletal Muscle-specific PGC-1α Overexpression Suppresses Atherosclerosis in Apolipoprotein E-Knockout Mice
    Yuki Shimba
    Hanako Togawa
    Nanami Senoo
    Masahiko Ikeda
    Noriyuki Miyoshi
    Akihito Morita
    Shinji Miura
    Scientific Reports, 9
  • [28] Gracilaria chorda attenuates obesity-related muscle wasting through activation of SIRT1/PGC1α in skeletal muscle of mice
    Yoo, Ahyoung
    Ahn, Jiyun
    Seo, Hyo Deok
    Hahm, Jeong-Hoon
    Kim, Min Jung
    Jung, Chang Hwa
    Ha, Tae Youl
    FOOD SCIENCE & NUTRITION, 2024, 12 (07): : 5077 - 5086
  • [29] SKELETAL MUSCLE-SPECIFIC PGC-1α OVEREXPRESSION PREVENTS ATHEROSCLEROSIS IN APOLIPOPROTEIN E-KNOCKOUT MICE
    Shimba, Yuki
    Togawa, Hanako
    Senoo, Nanami
    Ikeda, Masahiko
    Miyoshi, Noriyuki
    Morita, Akihito
    Miura, Shinji
    ATHEROSCLEROSIS SUPPLEMENTS, 2018, 32 : 17 - 18
  • [30] Skeletal Muscle-specific PGC-1α Overexpression Suppresses Atherosclerosis in Apolipoprotein E-Knockout Mice
    Shimba, Yuki
    Togawa, Hanako
    Senoo, Nanami
    Ikeda, Masahiko
    Miyoshi, Noriyuki
    Morita, Akihito
    Miura, Shinji
    SCIENTIFIC REPORTS, 2019, 9 (1)
12345