The transcription of the chitin synthase genes (chss) was cell cycle-regulated in Aspergillus nidulans and the expression pattern was classified into two groups. Group one, containing chsA and chsC, showed decreasing transcription level upon entry into the S-phase and no further variation during the remainder of the cell cycle. However, group two, containing chsB, chsD, and csmA, showed a sharp decrease of mRNA level upon entry into the G2-phase and an increase during the M-phase. Our results suggested that the chss, belonging to same group with the similar expression pattern during the cell cycle are functionally linked and that chsD may play a role in hyphal growth and development in A. nidulans.
机构:Penn State Univ, Coll Med, Weis Ctr Res, Henry Hood Res Program, Danville, PA 17822 USA
Ye, XS
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Lee, SL
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机构:Penn State Univ, Coll Med, Weis Ctr Res, Henry Hood Res Program, Danville, PA 17822 USA
Lee, SL
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Wolkow, TD
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机构:Penn State Univ, Coll Med, Weis Ctr Res, Henry Hood Res Program, Danville, PA 17822 USA
Wolkow, TD
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McGuire, SL
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机构:Penn State Univ, Coll Med, Weis Ctr Res, Henry Hood Res Program, Danville, PA 17822 USA
McGuire, SL
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Hamer, JE
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机构:Penn State Univ, Coll Med, Weis Ctr Res, Henry Hood Res Program, Danville, PA 17822 USA
Hamer, JE
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Wood, GC
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机构:Penn State Univ, Coll Med, Weis Ctr Res, Henry Hood Res Program, Danville, PA 17822 USA
Wood, GC
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Osmani, SA
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Penn State Univ, Coll Med, Weis Ctr Res, Henry Hood Res Program, Danville, PA 17822 USAPenn State Univ, Coll Med, Weis Ctr Res, Henry Hood Res Program, Danville, PA 17822 USA
机构:Penn State Univ, Coll Med, Weis Ctr Res, Henry Hood Res Program, Danville, PA 17822 USA
Ye, XS
;
Lee, SL
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机构:Penn State Univ, Coll Med, Weis Ctr Res, Henry Hood Res Program, Danville, PA 17822 USA
Lee, SL
;
Wolkow, TD
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机构:Penn State Univ, Coll Med, Weis Ctr Res, Henry Hood Res Program, Danville, PA 17822 USA
Wolkow, TD
;
McGuire, SL
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机构:Penn State Univ, Coll Med, Weis Ctr Res, Henry Hood Res Program, Danville, PA 17822 USA
McGuire, SL
;
Hamer, JE
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机构:Penn State Univ, Coll Med, Weis Ctr Res, Henry Hood Res Program, Danville, PA 17822 USA
Hamer, JE
;
Wood, GC
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机构:Penn State Univ, Coll Med, Weis Ctr Res, Henry Hood Res Program, Danville, PA 17822 USA
Wood, GC
;
Osmani, SA
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Penn State Univ, Coll Med, Weis Ctr Res, Henry Hood Res Program, Danville, PA 17822 USAPenn State Univ, Coll Med, Weis Ctr Res, Henry Hood Res Program, Danville, PA 17822 USA