A prospective trial comparing wireless capsule endoscopy and barium contrast series for small-bowel surveillance in hereditary G1 polyposis syndromes

被引:109
作者
Mata, A
Llach, J
Castells, A
Rovira, JM
Pellisé, M
Ginès, A
Fernández-Esparrach, G
Andreu, M
Bordas, JM
Piqué, JM
机构
[1] Inst Malalties Digest, Dept Radiol, Digest Endoscopy Unit, Dept Gastroenterol,Ctr Diagnost Imatge, Barcelona, Catalonia, Spain
[2] Univ Barcelona, Hosp Clin, Inst Invest Biomed August Pi & Sunyer, Barcelona, Spain
[3] Univ Autonoma Barcelona, Hosp Mar, Dept Gastroenterol, E-08003 Barcelona, Catalonia, Spain
关键词
D O I
10.1016/S0016-5107(05)00289-0
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background: Capsule endoscopy has demonstrated its clinical utility in the evaluation of the small bowel, and, accordingly, it has been suggested that it could be useful for the identification of small-intestinal polyps in patients with polyposis syndromes. The objective was to establish the effectiveness of wireless capsule endoscopy for detecting small-bowel polyps in patients with hereditary GI polyposis syndromes in comparison with barium contrast series. Methods: Consecutive patients with GI polyposis syndromes were included. Small-bowel follow-through series and capsule endoscopy were performed within 1 week, in a blind fashion. The number and the location of polyps were analyzed. Results: Twenty-four patients with familial adenomatous polyposis (n = 20) or Peutz-Jeghers syndrome (n = 4) were included. Capsule endoscopy detected small-bowel polyps in 7 of 24 patients (29%), whereas a barium contrast study identified small-intestinal polyps in only 3 of these 7 patients. In the 4 remaining patients, all of them with familial adenomatous polyposis, polyps detected by the capsule but missed in radiographic series were located at either ileum (2 patients), jejunum (1), or duodenum (1). No procedure-related complication was observed in any patient. Conclusions: Wireless capsule endoscopy is a highly accurate technique for the detection of small-bowel I polyps in patients with hereditary GI polyposis syndromes, and it represents a valuable alternative to barium contrast series in the surveillance of patients with Peutz-Jeghers syndrome.
引用
收藏
页码:721 / 725
页数:5
相关论文
共 22 条
[1]   Hereditary polyposis syndromes and hereditary non-polyposis colorectal cancer [J].
Allen, BA ;
Terdiman, JP .
BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY, 2003, 17 (02) :237-258
[2]   Colon cancer screening [J].
Burt, RW .
GASTROENTEROLOGY, 2000, 119 (03) :837-853
[3]   A prospective trial comparing small bowel radiographs and video capsule endoscopy for suspected small bowel disease [J].
Costamagna, G ;
Shah, SK ;
Riccioni, ME ;
Foschia, F ;
Mutignani, M ;
Perri, V ;
Vecchioli, A ;
Brizi, MG ;
Picciocchi, A ;
Marano, P .
GASTROENTEROLOGY, 2002, 123 (04) :999-1005
[4]  
de Mascarenhas-Saraiva MNG, 2003, ENDOSCOPY, V35, P865
[5]   Wireless capsule video endoscopy is a superior diagnostic tool in comparison to barium follow-through and computerized tomography in patients with suspected Crohn's disease [J].
Eliakim, R ;
Fischer, D ;
Suissa, A ;
Yassin, K ;
Katz, D ;
Guttman, N ;
Migdal, M .
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2003, 15 (04) :363-367
[6]   The first prospective controlled trial comparing wireless capsule endoscopy with push enteroscopy in chronic gastrointestinal bleeding [J].
Ell, C ;
Remke, S ;
May, A ;
Helou, L ;
Henrich, R ;
Mayer, G .
ENDOSCOPY, 2002, 34 (09) :685-689
[7]   Diagnosing small bowel Crohn's disease with wireless capsule endoscopy [J].
Fireman, Z ;
Mahajna, E ;
Broide, E ;
Shapiro, M ;
Fich, L ;
Sternberg, A ;
Kopelman, Y ;
Scapa, E .
GUT, 2003, 52 (03) :390-392
[8]  
Hartmann D, 2003, Z GASTROENTEROL, V41, P377
[9]   Wireless capsule endoscopy [J].
Iddan, G ;
Meron, G ;
Glukhovsky, A ;
Swain, P .
NATURE, 2000, 405 (6785) :417-417
[10]   Capsule endoscopy in the evaluation of patients with suspected small intestinal bleeding: results of a pilot study [J].
Lewis, BS ;
Swain, P .
GASTROINTESTINAL ENDOSCOPY, 2002, 56 (03) :349-353