Effects of Astroglia on Motor Neurons in Spinal Muscular Atrophy

被引：3
|
作者：
Verheijen, Bert M. [1 ,2 ]
机构：
[1] Univ Med Ctr Utrecht, Dept Translat Neurosci, Brain Ctr Rudolf Magnus, NL-3584 CG Utrecht, Netherlands
[2] Univ Med Ctr Utrecht, Dept Neurol & Neurosurg, Brain Ctr Rudolf Magnus, Utrecht, Netherlands
来源：
JOURNAL OF NEUROSCIENCE | 2017年 / 37卷 / 36期
关键词：
SCHWANN-CELLS; MOUSE MODEL; ASTROCYTES; SMN; PROTEIN; DEFECTS; TRANSCRIPTOME; RESTORATION; SEVERITY; RESCUE;
D O I：
10.1523/JNEUROSCI.1578-17.2017
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
引用
收藏
页码：8578 / 8580
页数：3
相关论文
共 50 条
  • [31] Astrocytes influence the severity of spinal muscular atrophy
    Rindt, Hansjoerg
    Feng, Zhihua
    Mazzasette, Chiara
    Glascock, Jacqueline J.
    Valdivia, David
    Pyles, Noah
    Crawford, Thomas O.
    Swoboda, Kathryn J.
    Patitucci, Teresa N.
    Ebert, Allison D.
    Sumner, Charlotte J.
    Ko, Chien-Ping
    Lorson, Christian L.
    HUMAN MOLECULAR GENETICS, 2015, 24 (14) : 4094 - 4102
  • [32] Advances and limitations for the treatment of spinal muscular atrophy
    Day, John W.
    Howell, Kelly
    Place, Amy
    Long, Kimberly
    Rossello, Jose
    Kertesz, Nathalie
    Nomikos, George
    BMC PEDIATRICS, 2022, 22 (01)
  • [33] Sense in Antisense Therapy for Spinal Muscular Atrophy
    MacKenzie, Alex
    NEW ENGLAND JOURNAL OF MEDICINE, 2012, 366 (08) : 761 - 763
  • [34] Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?
    Burghes, Arthur H. M.
    Beattie, Christine E.
    NATURE REVIEWS NEUROSCIENCE, 2009, 10 (08) : 597 - 609
  • [35] Spinal Muscular Atrophy: An Update
    Chang, Tracy
    Gieron-Korthals, Maria
    FETAL AND PEDIATRIC PATHOLOGY, 2011, 30 (02) : 130 - 136
  • [36] Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy
    Simon, Christian M.
    Van Alstyne, Meaghan
    Lotti, Francesco
    Bianchetti, Elena
    Tisdale, Sarah
    Watterson, D. Martin
    Mentis, George Z.
    Pellizzoni, Livio
    CELL REPORTS, 2019, 29 (12): : 3885 - +
  • [37] Converging Mechanisms of p53 Activation Drive Motor Neuron Degeneration in Spinal Muscular Atrophy
    Simon, Christian M.
    Dai, Ya
    Van Alstyne, Meaghan
    Koutsioumpa, Charalampia
    Pagiazitis, John G.
    Chalif, Joshua I.
    Wang, Xiaojian
    Rabinowitz, Joseph E.
    Henderson, Christopher E.
    Pellizzoni, Livio
    Mentis, George Z.
    CELL REPORTS, 2017, 21 (13): : 3767 - 3780
  • [38] Spinal astrocyte dysfunction drives motor neuron loss in late-onset spinal muscular atrophy
    Schmitt, Linda-Isabell
    David, Christina
    Steffen, Rebecca
    Hezel, Stefanie
    Roos, Andreas
    Schara-Schmidt, Ulrike
    Kleinschnitz, Christoph
    Leo, Markus
    Hagenacker, Tim
    ACTA NEUROPATHOLOGICA, 2023, 145 (05) : 611 - 635
  • [39] GEMINs: potential therapeutic targets for spinal muscular atrophy?
    Borg, Rebecca
    Cauchi, Ruben J.
    FRONTIERS IN NEUROSCIENCE, 2014, 8
  • [40] Future avenues for therapy development for spinal muscular atrophy
    Groen, Ewout J. N.
    EXPERT OPINION ON DRUG DISCOVERY, 2018, 13 (10) : 899 - 902
12345