Recommendations to improve lipid control. Consensus document of the Spanish Society of Cardiology

被引：34

作者：

Escobar, Carlos ^{[1
]}

Anguita, Manuel ^{[2
]}

Arrarte, Vicente ^{[3
]}

Barrios, Vivencio ^{[4
]}

Cequier, Angel ^{[5
]}

Cosin-Sales, Juan ^{[6
]}

Egocheaga, Isabel ^{[7
]}

Lopez de Sa, Esteban ^{[1
]}

Masana, Luis ^{[8
]}

Pallares, Vicente ^{[9
]}

Perez de Isla, Leopoldo ^{[10
]}

Pinto, Xavier ^{[11
]}

Gonzalez Juanatey, Jose Ramon ^{[12
]}

Luis Zamorano, Jose ^{[4
]}

机构：

[1] Hosp Univ La Paz, Serv Cardiol, P Castellana 261, Madrid 28046, Spain

[2] Hosp Reina Sofia, Serv Cardiol, Cordoba, Spain

[3] Hosp Gen Univ, Serv Cardiol, Alicante, Spain

[4] Hosp Univ Ramon y Cajal, Serv Cardiol, Madrid, Spain

[5] Hosp Univ Bellvitge, Serv Cardiol, Barcelona, Spain

[6] Hosp Arnau Vilanova, Serv Cardiol, Valencia, Spain

[7] Ctr Salud Isla Oza, Madrid, Spain

[8] Hosp Univ St Joan, Unitat Med Vasc & Metab, Tarragona, Spain

[9] Union Mutuas, Unidad Vigilancia Salud, Castellon de La Plana, Spain

[10] Hosp Univ Clin, Serv Cardiol, Madrid, Spain

[11] Hosp Univ Bellvitge, Serv Med Interna, Unidad Riesgo Vasc, Barcelona, Spain

[12] Univ Santiago de Compostela, Serv Cardiol, Hosp Clin, Santiago De Compostela, A Coruna, Spain

来源：

REVISTA ESPANOLA DE CARDIOLOGIA | 2020年 / 73卷 / 02期

关键词：

Ischemic heart disease; LDL-cholesterol; Secondary prevention; Lipid-lowering therapy; CORONARY-HEART-DISEASE; CARDIOVASCULAR EVENTS; LDL CHOLESTEROL; CLINICAL ENDOCRINOLOGISTS; MYOCARDIAL-INFARCTION; AMERICAN ASSOCIATION; RISK; MANAGEMENT; STATIN; SAFETY;

D O I：

10.1016/j.rec.2019.08.012

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The current control of low-density lipoprotein cholesterol among patients with atherosclerotic cardiovascular disease is very low and this is associated with an increase of cardiovascular outcomes. In addition, the latter this happens, the risk will be greater. This is mainly due to an insufficient use of the lipid-lowering therapy currently available. In fact, with current treatments (statins, ezetimibe and PCSK9 inhibitors), the majority of patients in secondary prevention should achieve low-density lipoprotein cholesterol goals. For these reasons, in this manuscript promoted by the Spanish Society of Cardiology we propose three simple and feasible decision-making algorithms that include the majority of clinical scenarios among patients with ischemic heart disease, with the double aim of attaining therapeutic goals in the majority of patients as soon as possible; in secondary prevention the magnitude of the benefit is risk- and time-dependent. (C) 2019 Sociedad Espanola de Cardiologia. Published by Elsevier Espana, S.L.U. All rights reserved.

引用

页码：161 / 167

页数：7

共 38 条

[1]

Aaue Asenjo Mota, 2019, HIPERTENS RIESGO VAS, DOI [10.1016/j.hipert.2019.04.001, DOI 10.1016/J.HIPERT.2019.04.001]

[2] The Risk of Cardiovascular Events After an Acute Coronary Event Remains High, Especially During the First Year, Despite Revascularization [J].

Abu-Assi, Emad ;

Lopez-Lopez, Andrea ;

Gonzalez-Salvado, Violeta ;

Redondo-Dieguez, Alfredo ;

Pena-Gil, Carlos ;

Bouzas-Cruz, Noelia ;

Raposeiras-Roubin, Sergio ;

Riziq-Yousef Abumuaileq, Rami ;

Garcia-Acuna, Jose M. ;

Gonzalez-Juanatey, Jose R. .

REVISTA ESPANOLA DE CARDIOLOGIA, 2016, 69 (01) :11-18

[3] Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials [J].

Baigent, C. ;

Blackwell, L. ;

Emberson, J. ;

Holland, L. E. ;

Reith, C. ;

Bhala, N. ;

Peto, R. ;

Barnes, E. H. ;

Keech, A. ;

Simes, J. ;

Collins, R. .

LANCET, 2010, 376 (9753) :1670-1681

[4] Cardiovascular risk profile and risk stratification of the hypertensive population attended by general practitioners and specialists in Spain.: The CONTROLRISK study [J].

Barrios, V. ;

Escobar, C. ;

Calderon, A. ;

Echarri, R. ;

Gonzalez-Pedel, V. ;

Ruilope, L. M. .

JOURNAL OF HUMAN HYPERTENSION, 2007, 21 (06) :479-485

[5]

Blasco M, 2017, CLIN INVEST ARTERIOS, V29, P218, DOI 10.1016/j.arteri.2017.06.003

[6] Very Low Levels of Atherogenic Lipoproteins and the Risk for Cardiovascular Events A Meta-Analysis of Statin Trials [J].

Boekholdt, S. Matthijs ;

Hovingh, G. Kees ;

Mora, Samia ;

Arsenault, Benoit J. ;

Amarenco, Pierre ;

Pedersen, Terje R. ;

LaRosa, John C. ;

Waters, David D. ;

DeMicco, David A. ;

Simes, R. John ;

Keech, Antony C. ;

Colquhoun, David ;

Hitman, Graham A. ;

Betteridge, John ;

Clearfield, Michael B. ;

Downs, John R. ;

Colhoun, Helen M. ;

Gotto, Antonio M., Jr. ;

Ridker, Paul M. ;

Grundy, Scott M. ;

Kastelein, John J. P. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2014, 64 (05) :485-494

[7] Association of LDL Cholesterol, Non-HDL Cholesterol, and Apolipoprotein B Levels With Risk of Cardiovascular Events Among Patients Treated With Statins A Meta-analysis [J].

Boekholdt, S. Matthijs ;

Arsenault, Benoit J. ;

Mora, Samia ;

Pedersen, Terje R. ;

LaRosa, John C. ;

Nestel, Paul J. ;

Simes, R. John ;

Durrington, Paul ;

Hitman, Graham A. ;

Welch, K. M. A. ;

DeMicco, David A. ;

Zwinderman, Aeilko H. ;

Clearfield, Michael B. ;

Downs, John R. ;

Tonkin, Andrew M. ;

Colhoun, Helen M. ;

Gotto, Antonio M., Jr. ;

Ridker, Paul M. ;

Kastelein, John J. P. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2012, 307 (12) :1302-1309

[8] OPTIMIZATION OF LIPID-LOWERING TREATMENT BEFORE DISCHARGE AFTER ACUTE MYOCARDIAL INFARCTION: THE ROUTINE APPLICATION OF A FRENCH CONSENSUS [J].

Camille, Buonvino ;

Ferrieres, Jean ;

Famier, Michel ;

Bruckert, Eric ;

Krempf, Michel ;

Tchaoussoff, Celine ;

Schiele, Francois .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2019, 73 (09) :191-191

[9] Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes [J].

Cannon, Christopher P. ;

Blazing, Michael A. ;

Giugliano, Robert P. ;

McCagg, Amy ;

White, Jennifer A. ;

Theroux, Pierre ;

Darius, Harald ;

Lewis, Basil S. ;

Ophuis, Ton Oude ;

Jukema, J. Wouter ;

De Ferrari, Gaetano M. ;

Ruzyllo, Witold ;

De Lucca, Paul ;

Im, KyungAh ;

Bohula, Erin A. ;

Reist, Craig ;

Wiviott, Stephen D. ;

Tershakovec, Andrew M. ;

Musliner, Thomas A. ;

Braunwald, Eugene ;

Califf, Robert M. .

NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (25) :2387-2397

[10]

Catapano AL, 2017, REV ESP CARDIOL, V70, pe1

← 1 2 3 4 →