Exogenous hormones and hereditary angioedema

被引:17
|
作者
Gompel, Anne [1 ,5 ]
Fain, Olivier [2 ,3 ,5 ]
Boccon-Gibod, Isabelle [4 ,5 ]
Gobert, Delphine [2 ,3 ,5 ]
Bouillet, Laurence [4 ,5 ]
机构
[1] Univ Paris 05, Gynecol, 123 BD Du Port Royal, F-75014 Paris, France
[2] Univ Paris 06, 184 Rue Faubourg St Antoine, F-75012 Paris, France
[3] Hop St Antoine, AP HP, Serv Med Interne, 184 Rue Faubourg St Antoine, F-75012 Paris, France
[4] Univ Grenoble, CHU Grenoble, Serv Med Interne, F-38043 Grenoble 09, France
[5] Natl Reference Ctr Angioedema CREAK, Paris, France
关键词
Bradykinin; C1; Inhibitor; Factor XII; Plasmin; Danazol; Contraception; Assisted reproductive technology; Menopause; Breast cancer; Prostate cancer; MOLECULAR-WEIGHT KININOGEN; ORAL-CONTRACEPTIVES; FACTOR-XII; REPLACEMENT THERAPY; BLOOD-PRESSURE; BRADYKININ; ESTROGEN; WOMEN; ETHINYLESTRADIOL; PHARMACOKINETICS;
D O I
10.1016/j.intimp.2019.106080
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Gonadal hormones, estrogen and androgen are strongly involved in the control of the bradykinin production. Estrogen may worsen whereas androgen can be part of the long-term prophylactic treatment. In this review, we will describe the potential impact of estrogen in the pathophysiology of hereditary angioedema (HAE). Then we will review the different hormone treatments and their implication on the course of HAE in women and men: contraception, Assisted Reproductive Technology (ART), menopause, hormone dependent cancers in women and men, treatment of hyperandrogenism in women.
引用
收藏
页数:6
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