Asymmetric catalytic C-H activation applied to the synthesis of syn-aldol products

被引：62

作者：

Davies, HML ^{[1
]}

Antoulinakis, EG ^{[1
]}

机构：

[1] SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 26期

关键词：

D O I：

10.1021/ol006671j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Rh-2(R-DOSP)(4)-catalyzed decomposition of methyl phenyldiazoacetate in the presence of tetraalkoxysilanes results in the asymmetric synthesis of syn-aldol products. This catalytic asymmetric intermolecular C-H activation proceeds by means of a rhodium-carbene-induced CH insertion.

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页码：4153 / 4156

页数：4

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