Acute disseminated encephalomyelitis in dengue viral infection

被引：14

作者：

Sulaiman, Wan Aliaa Wan ^{[1
,4
]}

Mat, Liyana Najwa Inche ^{[1
,4
]}

Hashim, Hasnur Zaman ^{[1
]}

Kee, Hoo Fan ^{[1
,4
]}

Mooi, Ching Siew ^{[2
,4
]}

Vasudevan, Ramachandran ^{[4
]}

Mohamed, Mohd Hazmi ^{[3
]}

Basri, Hamidon ^{[1
]}

机构：

[1] Univ Putra Malaysia, Fac Med & Hlth Sci, Dept Med, Serdang, Malaysia

[2] Univ Putra Malaysia, Fac Med & Hlth Sci, Dept Family Med, Serdang, Malaysia

[3] Univ Putra Malaysia, Fac Med & Hlth Sci, Dept Surg, Serdang, Malaysia

[4] Univ Putra Malaysia, Inst Gerontol, Serdang 43400, Selangor, Malaysia

来源：

JOURNAL OF CLINICAL NEUROSCIENCE | 2017年 / 43卷

关键词：

Dengue virus; Severe dengue; Encephalomyelitis; Acute disseminated; Nervous system disorders; Demyelinating diseases; CENTRAL-NERVOUS-SYSTEM; PEDIATRIC MULTIPLE-SCLEROSIS; NEUROLOGICAL MANIFESTATIONS; ATYPICAL MANIFESTATIONS; VIRUS-INFECTION; COMPLICATIONS; DISORDERS; DIAGNOSIS; CHILDREN;

D O I：

10.1016/j.jocn.2017.05.033

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Dengue is the most common arboviral disease affecting many countries worldwide. An RNA virus froth the flaviviridae family, dengue has four antigenically distinct serotypes (DEN-1-DEN-4). Neurological involvement in dengue can be classified into dengue encephalopathy immune-mediated syndromes, encephalitis, neuromuscular or dengue muscle dysfunction and neuro-ophthalmic involvement. Acute disseminated encephalomyelitis (ADEM) is an immune mediated acute demyelinating disorder of the central nervous system following recent infection or vaccination. This monophasic illness is characterised by multifocal white matter involvement. Many dengue studies and case reports have linked ADEM with dengue virus infection but the association is still not clear. Therefore, this article is to review and discuss concerning ADEM in dengue as an immune-medicated neurological complication; and the management strategy required based on recent literature. (C) 2017 Elsevier Ltd. All rights reserved.

引用

页码：25 / 31

页数：7

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