Maternal vaccination: a review of current evidence and recommendations

被引:88
作者
Etti, Melanie [1 ]
Calvert, Anna [1 ]
Galiza, Eva [1 ]
Lim, Suzy [1 ]
Khalil, Asma [2 ]
Le Doare, Kirsty [1 ]
Heath, Paul T. [1 ,3 ]
机构
[1] St Georges Univ London, Inst Infect & Immun, Paediat Infect Dis Res Grp, London, England
[2] St Georges Univ Hosp NHS Fdn Trust, Fetal Med Unit, Dept Obstet & Gynaecol, London, England
[3] St Georges Univ London, Vaccine Inst, London, England
关键词
COVID-19; vaccination; immunogenicity; maternal vaccination; neonates; safety; PNEUMOCOCCAL POLYSACCHARIDE VACCINE; RESPIRATORY SYNCYTIAL VIRUS; EVENT REPORTING SYSTEM; GROUP-B STREPTOCOCCUS; POSTEXPOSURE RABIES VACCINATION; PERTUSSIS-CONTAINING VACCINE; MIDDLE-INCOME COUNTRIES; ORAL CHOLERA VACCINE; PREGNANT-WOMEN; CONJUGATE VACCINE;
D O I
10.1016/j.ajog.2021.10.041
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Maternal vaccination is an effective means of protecting pregnant women, their fetuses, and infants from vaccine-preventable infections. Despite the availability of sufficient safety data to support the use of vaccines during pregnancy, maternal immunization remains an underutilized method of disease prevention, often because of concerns from both healthcare providers and pregnant women about vaccine safety. Such concerns have been reflected in the low uptake of the COVID-19 vaccine among pregnant women seen in many parts of the world. Here, we present an update of the current recommendations for the use of vaccines during pregnancy, including the evidence supporting the use of novel vaccine platforms. We also provide an overview of the data supporting the use of COVID-19 vaccines in pregnancy and an update of the status of vaccines that are currently under development for use in pregnant women.
引用
收藏
页码:459 / 474
页数:16
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