Moving exercise research in multiple sclerosis forward (the MoXFo initiative): Developing consensus statements for research

被引:51
作者
Dalgas, Ulrik [1 ]
Hvid, Lars G. [1 ]
Kwakkel, Gert [2 ,3 ,4 ]
Motl, Robert W. [5 ]
de Groot, Vincent [6 ,7 ,8 ]
Feys, Peter [9 ]
Op't Eijnde, Bert [9 ]
Coote, Susan [10 ]
Beckerman, Heleen [6 ,7 ,8 ]
Pfeifer, Klaus [11 ]
Streber, Rene [11 ,12 ]
Peters, Stefan [13 ]
Riemann-Lorenz, Karin [14 ]
Rosenkranz, Sina Catherine [14 ,15 ]
Centonze, Diego [16 ]
Van Asch, Paul [17 ]
Bansi, Jens [18 ]
Sandroff, Brian M. [5 ]
Pilutti, Lara A. [19 ]
Ploughman, Michelle [20 ]
Freeman, Jennifer [21 ]
Paul, Lorna [22 ]
Dawes, Helen [23 ]
Romberg, Anders [24 ]
Kalron, Alon [25 ,26 ]
Stellmann, Jan-Patrick [27 ,28 ]
Friese, Manuel A. [14 ]
Heesen, Christoph [14 ,15 ]
机构
[1] Aarhus Univ, Dept Publ Hlth, Sect Sport Sci, DK-8000 Aarhus, Denmark
[2] Vrije Univ Amsterdam, Dept Rehabil Med, Amsterdam UMC, Amsterdam Movement Sci,Amsterdam Neurosci, Amsterdam, Netherlands
[3] Northwestern Univ, Feinberg Sch Med, Dept Phys Therapy & Human Movement Sci, Chicago, IL 60611 USA
[4] Amsterdam Rehabil Res Ctr, Dept Neurorehabil, Amsterdam, Netherlands
[5] Univ Alabama Birmingham, Dept Phys Therapy, Birmingham, AL USA
[6] Vrije Univ Amsterdam, Med Ctr, Dept Rehabil Med, Amsterdam, Netherlands
[7] Vrije Univ Amsterdam, MS Ctr Amsterdam, Med Ctr, Amsterdam, Netherlands
[8] Vrije Univ Amsterdam, Med Ctr, Amsterdam Publ Hlth Res Inst, Amsterdam, Netherlands
[9] Hasselt Univ, Fac Rehabil Sci, REVAL Rehabil Res Ctr, Diepenbeek, Belgium
[10] Univ Limerick, Fac Educ & Hlth Sci, Sch Allied Hlth, Limerick, Ireland
[11] Friedrich Alexander Univ Erlangen Nurnberg FAU, Dept Sport Sci, Div Exercise & Hlth, Erlangen, Germany
[12] Deutsch Verband Gesundheitssport & Sporttherapie, Hurth, Germany
[13] Deutsch Verband Gesundheitssport & Sporttherapie, Hurth, Hurth, Germany
[14] Univ Klinikum Hamburg Eppendorf, Inst Neuroimmunol & Multiple Sklerose, Hamburg, Germany
[15] Univ Klinikum Hamburg Eppendorf, Klin & Poliklin Neurol, Hamburg, Germany
[16] IRCCS Neuromed, Unit Neurol, Pozzilli, Italy
[17] Fit Physiotherapy Ctr, Kontich, Belgium
[18] Klin Valens, Rehabil Klin Valens, Dept Neurol, Valens, Switzerland
[19] Univ Ottawa, Interdisciplinary Sch Hlth Sci, Ottawa, ON, Canada
[20] Mem Univ Newfoundland, Fac Med, St John, NF, Canada
[21] Univ Plymouth, Fac Hlth Med Dent & Human Sci, Plymouth, Devon, England
[22] Glasgow Caledonian Univ, Sch Hlth & Life Sci, Glasgow, Lanark, Scotland
[23] Oxford Brookes Univ, Sch Life Sci, Movement Sci Grp, Oxford, England
[24] Masku Neurol Rehabil Ctr, Masku, Finland
[25] Tel Aviv Univ, Sackler Fac Med, Dept Phys Therapy, Stanley Steyer Sch Hlth Profess, Tel Aviv, Israel
[26] Tel Aviv Univ, Sagol Sch Neurosci, Tel Aviv, Israel
[27] CEMEREM, Hop la Timone, AP HM, Marseille, France
[28] Aix Marseille Univ, CNRS, CRMBM, UMR 7339, Marseille, France
关键词
Consensus; exercise; rehabilitation; recommendations; multiple sclerosis; PHYSICAL-ACTIVITY; REHABILITATION; DETERMINANTS; GUIDELINES; ADHERENCE;
D O I
10.1177/1352458520910360
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Exercise as a subset of physical activity is a cornerstone in the management of multiple sclerosis (MS) based on its pleotropic effects. There is an exponential increase in the quantity of research on exercise in MS, yet a number of barriers associated with study content and quality hamper rapid progress in the field. To address these barriers and accelerate discovery, a new international partnership of MS-related experts in exercise has emerged with the goal of advancing the research agenda. As a first step, the expert panel met in May 2018 and identified the most urgent areas for moving the field forward, and discussed the framework for such a process. This led to identification of five themes, namely "Definitions and terminology," "Study methodology," "Reporting and outcomes," "Adherence to exercise," and "Mechanisms of action." Based on the identified themes, five expert groups have been formed, that will further (a) outline the challenges per theme and (b) provide recommendations for moving forward. We aim to involve and collaborate with people with MS/MS organizations (e.g. Multiple Sclerosis International Federation (MSIF) and European Multiple Sclerosis Platform (EMSP)) in all of these five themes. The generation of this thematic framework with multi-expert perspectives can bolster the quality and scope of exercise studies in MS that may ultimately improve the daily lives of people with MS.
引用
收藏
页码:1303 / 1308
页数:6
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