Clinical Correlates of Quality of Life in Tourette Syndrome

被引：93

作者：

Eddy, Clare M. ^{[1
]}

Cavanna, Andrea E. ^{[1
,2
]}

Gulisano, Mariangela ^{[3
]}

Agodi, Antonella ^{[3
,4
]}

Barchitta, Martina ^{[3
,4
]}

Cali, Paola ^{[3
]}

Robertson, Mary M. ^{[5
,6
]}

Rizzo, Renata ^{[3
]}

机构：

[1] Barberry Natl Ctr Mental Hlth, Dept Neuropsychiat, Birmingham B15 2FG, W Midlands, England

[2] UCL, Inst Neurol, Sobell Dept Motor Neurosci & Movement Disorders, London, England

[3] Univ Catania, Dept Pediat, Sect Child Neurol & Psychiat, Catania, Italy

[4] Univ Catania, Dept Biomed Sci, Catania, Italy

[5] Univ London St Georges Hosp, Sch Med, London SW17 0RE, England

[6] UCL, Dept Mental Hlth Sci, London, England

来源：

MOVEMENT DISORDERS | 2011年 / 26卷 / 04期

关键词：

Tourette syndrome; tics; quality of life; obsessive compulsive disorder; attention deficit hyperactivity disorder; SCALE; VALIDATION; CHILDREN; IMPACT; QOL;

D O I：

10.1002/mds.23434

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Tourette syndrome (TS) is a neurodevelopmental disorder involving tics, which is frequently accompanied by comorbid obsessive compulsive (OCD) or attention deficit hyperactivity disorder (ADHD). Individuals with TS often report poor quality of life (QoL) in comparison with the general population. This study investigated the clinical correlates of QoL in young people with TS using a self-report multidimensional QoL measure, and a range of clinical scales used to assess tic severity and the symptoms of anxiety, depression, OCD, ADHD and other emotional and behavioral symptoms. Symptoms of depression, OCD, and ADHD appeared to have a widespread negative impact on QoL, but poorer QoL was not associated with increased tic severity. Greater emotional and behavioral difficulties, including symptoms of OCD, were among the best predictors of poor QoL in young people with TS. (C) 2010 Movement Disorder Society

引用

页码：735 / 738

页数：4