Highly Efficient Antibacterial Surface Grafted with a Triclosan-Decorated Poly(N-Hydroxyethylacrylamide) Brush

被引：63
|
作者：
Wu, Hai-Xia [1 ,2 ]
Tan, Lei [1 ]
Tang, Zhao-Wen [1 ]
Yang, Mei-Yan [1 ]
Xiao, Jian-Yun [1 ]
Liu, Chuan-Jun [1 ]
Zhuo, Ren-Xi [1 ]
机构：
[1] Wuhan Univ, Coll Chem & Mol Sci, Key Lab Biomed Polymers, Minist Educ, Wuhan 430072, Hubei, Peoples R China
[2] Luoyang Normal Univ, Coll Chem & Chem Engn, Luoyang 471022, Henan, Peoples R China
来源：
ACS APPLIED MATERIALS & INTERFACES | 2015年 / 7卷 / 12期
基金：
中国国家自然科学基金;
关键词：
antibacterial surface; poly(N-hydroxyethylacrylamide); surface grafting; triclosan; resistance to bacterial adhesion; polymer brush; TRANSFER-RADICAL POLYMERIZATION; ORGANIC HYBRID COATINGS; ANTIFOULING COATINGS; BIOFILM FORMATION; STAINLESS-STEEL; BLOCK-COPOLYMER; IN-VITRO; RESISTANCE; POLYMERS; BIOCORROSION;
D O I：
10.1021/acsami.5b01210
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
This work presented a highly efficient antibacterial Ti-surface which was grafted with poly(N-hydroxyethylacrylamide) (PHEAA) brush and further decorated with triclosan (TCS). The modified surfaces were characterized using contact angle measurements, X-ray photoelectron spectroscopy, and attenuated total reflectance Fourier transform infrared. The antibacterial performance of the modified surfaces was evaluated using the Streptococcus mutans and Actinomyces naeslundii attachment test. The Ti surface with PHEAA brush (Ti-PHEAA) was able to resist the adhesion of the bacteria, while the TCS-decorated Ti surface (Ti-TCS) showed the capability of killing the bacteria adhered on the surface. As we coupled the TCS to the PHEAA brush, the surface showed highly efficient antibacterial performance due to the combination of the resistance to the bacteria adhesion and its activity of killing bacteria.
引用
收藏
页码：7008 / 7015
页数：8
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