The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance

被引：117

作者：

Valdes, Ana M. ^{[1
,2
]}

Evangelou, Evangelos ^{[3
]}

Kerkhof, Hanneke J. M. ^{[4
,5
]}

Tamm, Agu ^{[6
]}

Doherty, Sally A. ^{[7
]}

Kisand, Kalle ^{[6
,8
]}

Tamm, Ann ^{[9
]}

Kerna, Irina ^{[6
]}

Uitterlinden, Andre ^{[4
,5
]}

Hofman, Albert ^{[9
]}

Rivadeneira, Fernando ^{[4
,5
]}

Cooper, Cyrus ^{[10
,11
]}

Dennison, Elaine M. ^{[10
]}

Zhang, Weiya ^{[7
]}

Muir, Kenneth R. ^{[12
]}

Ioannidis, John P. A. ^{[3
]}

Wheeler, Margaret ^{[7
]}

Maciewicz, Rose A. ^{[13
]}

van Meurs, Joyce B. ^{[4
,5
]}

Arden, Nigel K. ^{[10
,11
]}

Spector, Tim D. ^{[1
,2
]}

Doherty, Michael ^{[7
]}

机构：

[1] Kings Coll London, St Thomas Hosp, Dept Twin Res, London SE1 7EH, England

[2] Kings Coll London, St Thomas Hosp, Genet Epidemiol Unit, London SE1 7EH, England

[3] Univ Ioannina, Sch Med, Dept Hyg & Epidemiol, GR-45110 Ioannina, Greece

[4] Erasmus MC, Dept Internal Med, Rotterdam, Netherlands

[5] NGI, Leiden, Netherlands

[6] Univ Tartu, Dept Internal Med, EE-50090 Tartu, Estonia

[7] Univ Nottingham, City Hosp Nottingham, Acad Rheumatol, Nottingham NG7 2RD, England

[8] Univ Tartu, Immunol Grp, Inst Gen & Mol Pathol, EE-50090 Tartu, Estonia

[9] Univ Tartu, Dept Sports Med & Rehabil, EE-50090 Tartu, Estonia

[10] MRC Epidemiol Resource Ctr, Southampton, Hants, England

[11] Univ Oxford, Musculoskeletal Biomed Res Unit, Oxford, England

[12] Univ Warwick, Warwick Med Sch, Hlth Sci Res Inst, Warwick, England

[13] AstraZeneca, Charnwood R&D, Resp & Inflammat Res Area, Loughborough, Leics, England

来源：

ANNALS OF THE RHEUMATIC DISEASES | 2011年 / 70卷 / 05期

基金：

英国医学研究理事会;

关键词：

SUSCEPTIBILITY;

D O I：

10.1136/ard.2010.134155

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：873 / U308

页数：3

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