Synthesis of Ca,Y-zirconia/hydroxyapatite nanoparticles and composites

被引：42

作者：

Castkova, K. ^{[1
]}

Hadraba, H. ^{[2
]}

Matousek, A. ^{[1
]}

Roupcova, P. ^{[1
]}

Chlup, Z. ^{[2
]}

Novotna, L. ^{[1
]}

Cihlar, J. ^{[1
]}

机构：

[1] Brno Univ Technol, CEITEC Cent European Inst Technol, Tech 10, Brno 61600, Czech Republic

[2] Acad Sci Czech Republic, Inst Phys Mat, CEITEC IPM Cent European Inst Technol, Zizkova 513-22, Brno 61662, Czech Republic

来源：

JOURNAL OF THE EUROPEAN CERAMIC SOCIETY | 2016年 / 36卷 / 12期

关键词：

Zirconia; Hydroxyapatite; Composite; Bioactivity; Mechanical properties; HYDROXYAPATITE-ZIRCONIA COMPOSITES; PARTIALLY-STABILIZED ZIRCONIA; INCREASED OSTEOBLAST ADHESION; MECHANICAL-PROPERTIES; SINTERED HYDROXYAPATITE; NANOPHASE CERAMICS; DOPED ZIRCONIA; MICROSTRUCTURE; BIOACTIVITY; TRANSFORMATION;

D O I：

10.1016/j.jeurceramsoc.2015.12.045

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Zirconia/hydroxyapatite composites were prepared by mixing hydroxyapatite (HA) and ZrO2 nanoparticles were prepared by precipitation synthesis. Nanoparticle composites with microporous structure and with a grain size of up to 10 mu m and a density of 94% were obtained. Due to the diffusion of Ca ions from HA to ZrO2, phase transformations took place in the composites during sintering. HA decomposed into a mixture of HA and calcium phosphates and simultaneously calcium zirconate was formed. Hardness and modulus of elasticity decreased with increasing porosity of the ZrO2/HA composites. The Ca-ZrO2/HA composites showed a higher bioactivity in simulated body fluid (SBF) testing than those of Y-ZrO2/HA. The osteoblast cells adhered more extensively to the Ca-ZrO2/HA composites than to the Y-ZrO2/HA ones. The effect of the microstructure and the chemical composition has the mechanical and biological properties could be used to optimize the mechanical and biological acceptability of the composites in bone repairs. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：2903 / 2912

页数：10

共 49 条

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