The role of QSAR in dopamine interactions

被引：11
|
作者：
Hansch, C [1 ]
Verma, RP [1 ]
Kurup, A [1 ]
Mekapati, SB [1 ]
机构：
[1] Pomona Coll, Dept Chem, Claremont, CA 91711 USA
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2005年 / 15卷 / 08期
关键词：
dopamine receptors; QSAR; hydrophobicity; molar refractivity; Verloop's sterimol parameters; hammett parameters;
D O I：
10.1016/j.bmcl.2005.02.012
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Dopamine receptor blockers have been used for the treatment of schizophrenia for many years. We have developed 22 quantitative structure activity relationships (QSAR) for different sets of compounds to understand chemical-biological interactions governing their activities toward dopamine receptors. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2149 / 2157
页数：9
相关论文
共 50 条
  • [31] Dopamine's role
    Gray, JA
    Young, AMJ
    Joseph, MH
    SCIENCE, 1997, 278 (5343) : 1548 - 1549
  • [32] Dual role for dopamine
    Fiona Carr
    Nature Reviews Neuroscience, 2016, 17 : 2 - 3
  • [33] The role for dopamine agonists
    Pellicer, A.
    Gomez, R.
    Garcia-Velasco, J.
    Simon, C.
    HUMAN REPRODUCTION, 2012, 27
  • [34] The role of dopamine in migraine
    Barbanti, P
    Rum, A
    Cerbo, R
    CONFINIA CEPHALALGICA, 1999, 8 (04): : 143 - 148
  • [35] THE ROLE OF DOPAMINE IN VOMITING
    BACKES, G
    FORTSCHRITTE DER MEDIZIN, 1986, 104 (08) : 177 - 180
  • [36] ROLE OF DOPAMINE IN ADDICTION
    GIRDHAR, A
    MANSURI, SM
    GOYAL, RK
    DAVE, KC
    PSYCHOPHARMACOLOGY, 1990, 101 : S21 - S21
  • [37] The expanding role of dopamine
    Doll, Bradley B.
    Daw, Nathaniel D.
    ELIFE, 2016, 5
  • [38] The role of dopamine in depression
    Corrigan, MH
    INTERNATIONAL JOURNAL OF PSYCHOLOGY, 2000, 35 (3-4) : 98 - 98
  • [39] ROLE OF DOPAMINE IN DEPRESSION
    MCCLURE, DJ
    CANADIAN PSYCHIATRIC ASSOCIATION JOURNAL, 1973, 18 (04): : 309 - 312
  • [40] The role of dopamine in epilepsy
    Starr, MS
    SYNAPSE, 1996, 22 (02) : 159 - 194
12345