Systematic review and meta-analysis of cyclodiene insecticides and breast cancer

被引：20

作者：

Khanjani, Narges ^{[1
]}

Hoving, Jan Lucas ^{[1
]}

Forbes, Andrew Benjamin ^{[1
]}

Sim, Malcolm Ross ^{[1
]}

机构：

[1] Monash Univ, Alfred Hosp, Cent & Eastern Clin Sch, Dept Epidemiol & Prevent Med, Melbourne, Vic 3004, Australia

来源：

JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS | 2007年 / 25卷 / 01期

关键词：

breast cancer; cyclodiene; meta-analysis; organochlorine; systematic review;

D O I：

10.1080/10590500701201711

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Cyclodienes are a group of organochlorine pesticides that have been the focus of increasing numbers of breast cancer etiology studies in recent years. The aim of this systematic review and meta-analysis was to summarize and pool the results of breast cancer and cyclodiene insecticide contamination studies. We used databases from 1966 to 7/2006 and included 21 case-control studies. Pooled odds ratios or differences in means as geometric means ratios were calculated. Meta-analysis of the chemicals did not reveal any statistically significant association except for heptachlor. The heterogeneity among the different studies and the methodology limitations are discussed.

引用

页码：23 / 52

页数：30

共 62 条

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