New insights into the control of cell growth; The role of the Axl family

被引:50
作者
Crosier, KE
Crosier, PS
机构
[1] Department of Molecular Medicine, School of Medicine, University of Auckland
[2] Department of Molecular Medicine, School of Medicine, University of Auckland, Auckland
关键词
receptor tyrosine kinase subfamily; growth-arrest-specific gene 6; tumorigenesis;
D O I
10.1080/00313029700169744
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Axl, Dtk and Mer are recently described receptors that constitute a new receptor tyrosine kinase subfamily. They bind the vitamin K-dependent protein growth-arrest-specific gene 6 (Gas6) that is structurally related to the anticoagulation factor protein S. Studies suggest a role for these receptors in developmental processes, in the function of the hematopoietic and nervous systems and in tumorigenesis.
引用
收藏
页码:131 / 135
页数:5
相关论文
共 43 条
[1]  
BELLOSTA P, 1995, MOL CELL BIOL, V15, P614
[2]  
BIESECKER LG, 1995, ONCOGENE, V10, P2239
[3]   RECEPTOR TYROSINE KINASES EXPRESSED IN METASTATIC COLON-CANCER [J].
CRAVEN, RJ ;
XU, LH ;
WEINER, TM ;
FRIDELL, YW ;
DENT, GA ;
SRIVASTAVA, S ;
VARNUM, B ;
LIU, ET ;
CANCE, WG .
INTERNATIONAL JOURNAL OF CANCER, 1995, 60 (06) :791-797
[4]   ISOLATION AND CHARACTERIZATION OF THE HUMAN DTK RECEPTOR TYROSINE KINASE [J].
CROSIER, KE ;
HALL, LR ;
LEWIS, PM ;
MORRIS, CM ;
WOOD, CR ;
MORRIS, JC ;
CROSIER, PS .
GROWTH FACTORS, 1994, 11 (02) :137-144
[5]  
Crosier PS, 1996, EXP HEMATOL, V24, P318
[6]   IDENTIFICATION OF A NOVEL RECEPTOR TYROSINE KINASE EXPRESSED IN ACUTE MYELOID LEUKEMIC BLASTS [J].
CROSIER, PS ;
HALL, LR ;
VITAS, MR ;
LEWIS, PM ;
CROSIER, KE .
LEUKEMIA & LYMPHOMA, 1995, 18 (5-6) :443-449
[7]   ISOLATION OF A RECEPTOR TYROSINE KINASE (DTK) FROM EMBRYONIC STEM-CELLS - STRUCTURE, GENETIC-MAPPING AND ANALYSIS OF EXPRESSION [J].
CROSIER, PS ;
LEWIS, PM ;
HALL, LR ;
VITAS, MR ;
MORRIS, CM ;
BEIER, DR ;
WOOD, CR ;
CROSIER, KE .
GROWTH FACTORS, 1994, 11 (02) :125-136
[8]  
DAHLBACK B, 1990, J BIOL CHEM, V265, P8127
[9]  
DAI W, 1994, ONCOGENE, V9, P975
[10]   INFLAMMATION - THEYRE NOT JUST FOR CLOTS ANYMORE [J].
ESMON, CT .
CURRENT BIOLOGY, 1995, 5 (07) :743-746