Extracorporeal membrane oxygenation and paracorporeal lung assist devices as a bridge to pediatric lung transplantation

被引:9
作者
Chiel, Laura E. [1 ]
Winthrop, Zachary A. [2 ]
Fynn-Thompson, Francis [3 ]
Midyat, Levent [1 ]
机构
[1] Harvard Med Sch, Div Pulm Med, Boston Childrens Hosp, Boston, MA 02115 USA
[2] Harvard Med Sch, Dept Pediat, Boston Childrens Hosp, Boston, MA 02115 USA
[3] Harvard Med Sch, Dept Cardiac Surg, Boston Childrens Hosp, Boston, MA 02115 USA
关键词
bridging; children; ECMO; lung transplantation; paracorporeal lung assist devices; OUTCOMES; SUPPORT; EXPERIENCE; CHILDREN; PATIENT; TIME; ECMO;
D O I
10.1111/petr.14289
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Background "Bridging" is a term used to describe the implementation of various treatment modalities to improve waitlist survival while a patient awaits lung transplantation. ECMO and PLAD are technologies used to bridge patients to lung transplantation. ECMO and PLAD are cardiopulmonary support systems that help move blood forward while using an artificial membrane to remove CO2 from and add O-2 to the blood. Recent studies showed that these technologies are increasingly effective in bridging patients to lung transplantation, especially with optimizing patient selection, implementing physical rehabilitation and ambulation goals, standardization of management decisions, and increasing staff experience, among other considerations. We review these technologies, their roles as bridges to pediatric lung transplantation, as well as indications, contraindications, complications, and mortality rates. Conclusion Finally, we discuss the existing knowledge gaps and areas for future research to improve patient outcomes and understanding of lung assist devices.
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页数:8
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