Glyco-functionalised quantum dots and their progress in cancer diagnosis and treatment

被引：14

作者：

Ashree, Jayshree ^{[1
]}

Wang Qi ^{[2
]}

Chao Yimin ^{[1
]}

机构：

[1] Univ East Anglia, Sch Chem, Norwich NR4 7TJ, Norfolk, England

[2] Univ East Anglia, Norwich Med Sch, Norwich NR4 7TJ, Norfolk, England

来源：

FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING | 2020年 / 14卷 / 03期

关键词：

carbohydrate; leptin; glyco-functionalised QD; bioimaging; cancer diagnosis and treatment; IMMOBILIZED FLUORESCENT NANOPARTICLES; CAPPED SILICON NANOPARTICLES; PROBING LECTIN; RECOGNITION; TOXICITY; CYTOTOXICITY; MULTIVALENCY; ANGIOGENESIS; CONJUGATION; LUMINESCENT;

D O I：

10.1007/s11705-019-1863-7

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Despite all major breakthroughs in recent years of research, we are still unsuccessful to effectively diagnose and treat cancer that has express and metastasizes. Thus, the development of a novel approach for cancer detection and treatment is crucial. Recent progress in Glyconanotechnology has allowed the use of glycans and lectins as bio-functional molecules for many biological and biomedical applications. With the known advantages of quantum dots (QDs) and versatility of carbohydrates and lectins, Glyco-functionalised QD is a new prospect in constructing biomedical imaging platform for cancer behaviour study as well as treatment. In this review, we aim to describe the current utilisation of Glyco-functionalised QDs as well as their future prospective to interpret and confront cancer.

引用

页码：365 / 377

页数：13

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