Glyco-functionalised quantum dots and their progress in cancer diagnosis and treatment

被引:14
作者
Ashree, Jayshree [1 ]
Wang Qi [2 ]
Chao Yimin [1 ]
机构
[1] Univ East Anglia, Sch Chem, Norwich NR4 7TJ, Norfolk, England
[2] Univ East Anglia, Norwich Med Sch, Norwich NR4 7TJ, Norfolk, England
关键词
carbohydrate; leptin; glyco-functionalised QD; bioimaging; cancer diagnosis and treatment; IMMOBILIZED FLUORESCENT NANOPARTICLES; CAPPED SILICON NANOPARTICLES; PROBING LECTIN; RECOGNITION; TOXICITY; CYTOTOXICITY; MULTIVALENCY; ANGIOGENESIS; CONJUGATION; LUMINESCENT;
D O I
10.1007/s11705-019-1863-7
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
Despite all major breakthroughs in recent years of research, we are still unsuccessful to effectively diagnose and treat cancer that has express and metastasizes. Thus, the development of a novel approach for cancer detection and treatment is crucial. Recent progress in Glyconanotechnology has allowed the use of glycans and lectins as bio-functional molecules for many biological and biomedical applications. With the known advantages of quantum dots (QDs) and versatility of carbohydrates and lectins, Glyco-functionalised QD is a new prospect in constructing biomedical imaging platform for cancer behaviour study as well as treatment. In this review, we aim to describe the current utilisation of Glyco-functionalised QDs as well as their future prospective to interpret and confront cancer.
引用
收藏
页码:365 / 377
页数:13
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