Synthesis, characterization polymerization and antibacterial properties of novel thiophene substituted acrylamide

被引：15

作者：

Elsabee, Maher Z. ^{[2
]}

Ali, Eman A. ^{[2
]}

Mokhtar, Samia M. ^{[1
]}

Eweis, Mohamed ^{[3
]}

机构：

[1] Ein Shams Univ, Coll Women, Fac Sci, Dept Chem, Cairo, Egypt

[2] Cairo Univ, Fac Sci, Dept Chem, Cairo 12613, Egypt

[3] Cairo Univ, Fac Sci, Dept Bot, Cairo 12613, Egypt

来源：

REACTIVE & FUNCTIONAL POLYMERS | 2011年 / 71卷 / 12期

关键词：

Thiophene; Acrylamide derivative; Methyl methacrylate; Vinyl acetate; Vinyl ether; Monomer reactivity ratios; Thermogravimetric analysis; Biological activity; VINYL-ACETATE; DERIVATIVES; COPOLYMERS; REACTIVITY; INHIBITORS; CHITOSAN; ESTER;

D O I：

10.1016/j.reactfunctpolym.2011.08.006

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Ethyl 2-acrylamido-4,5,6,7-tetrahydrobenzo [b] thiophene-3-carboxylate (ETTCA) has been synthesized and its structure has been elucidated by elemental analysis and spectral tools. Free radical polymerization of (ETTCA) has been conducted in several solvents using azobisisobutyronitrile (AIBN) as an initiator. The kinetic parameters of polymerization of the ETTCA were investigated, and it was found that the polymerization reaction follows the conventional free radical scheme. The overall activation energy of polymerization Delta E was determined (Delta E = 45.11 kJ mol(-1)). The copolymerization of ETTCA with three conventional monomers was carried out in dioxane at 65 degrees C. The monomer reactivity ratios for the copolymerization of ETTCA with methyl methacrylate (MMA), vinyl acetate (VA) and vinyl ether (VE) were calculated. Thermal stability of the ETTCA polymer and its copolymers were investigated by thermogravimetric analysis. It has been found that the prepared polymer (PETTCA) and its copolymers with VA have moderate biological activity and highly dependent on the copolymer composition. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：1187 / 1194

页数：8

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