Gene therapy targets sickle-cell disease

被引:0
|
作者
Nowogrodzki, Anna
机构
关键词
Diseases; Gene therapy; Medical research; Stem cells;
D O I
10.1038/d41586-018-07646-w
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The research is promising, but a true cure for this painful condition could be years away.
引用
收藏
页码:S12 / S13
页数:1
相关论文
共 50 条
  • [31] Progress toward safe and effective gene therapy for β-thalassemia and sickle cell disease
    Lebensburger, Jeffrey
    Persons, Derek A.
    CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT, 2008, 11 (02) : 225 - 232
  • [32] Gene and cell therapy for heart disease
    Graham, RM
    Bishopric, NH
    Webster, KA
    IUBMB LIFE, 2002, 54 (02) : 59 - 66
  • [33] Gene therapy in the fight against pediatric blood disorders: sickle cell disease and β-thalassemia
    Hu, Wei
    Wang, Bingyuan
    Song, Guowei
    Wang, Xiaojing
    Wang, Xiaoyun
    DRUGS OF THE FUTURE, 2022, 47 (06) : 443 - 456
  • [34] Emerging Genetic Therapy for Sickle Cell Disease
    Orkin, Stuart H.
    Bauer, Daniel E.
    ANNUAL REVIEW OF MEDICINE, VOL 70, 2019, 70 : 257 - 271
  • [35] Substitutions in the subunits of sickle-cell hemoglobin improve oxidative stability and increase the delay time of sickle-cell fiber formation
    Meng, Fantao
    Kassa, Tigist
    Strader, Michael Brad
    Soman, Jayashree
    Olson, John S.
    Alayash, Abdu I.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 294 (11) : 4145 - 4159
  • [36] Primary caregiver decision-making in hematopoietic cell transplantation and gene therapy for sickle cell disease
    Sinha, Cynthia B.
    Bakshi, Nitya
    Ross, Diana
    Loewenstein, George
    Krishnamurti, Lakshmanan
    PEDIATRIC BLOOD & CANCER, 2021, 68 (01)
  • [37] Under the hood: The molecular biology driving gene therapy for the treatment of sickle cell disease
    Waldron, Evan
    Tanhehco, Yvette C.
    TRANSFUSION AND APHERESIS SCIENCE, 2022, 61 (05)
  • [38] A systematic review comparing allogeneic hematopoietic stem cell transplant to gene therapy in sickle cell disease
    Rotin, Lianne E. E.
    Viswabandya, Auro
    Kumar, Rajat
    Patriquin, Christopher J. J.
    Kuo, Kevin H. M.
    HEMATOLOGY, 2023, 28 (01)
  • [39] Why the Middle East is a sickle-cell hotspot
    Benjamin Plackett
    Nature, 2021, 596 (7873) : S16 - S16
  • [40] A Universal Approach to Correct Various HBB Gene Mutations in Human Stem Cells for Gene Therapy of Beta-Thalassemia and Sickle Cell Disease
    Cai, Liuhong
    Bai, Hao
    Mahairaki, Vasiliki
    Gao, Yongxing
    He, Chaoxia
    Wen, Yanfei
    Jin, You-Chuan
    Wang, You
    Pan, Rachel L.
    Qasba, Armaan
    Ye, Zhaohui
    Cheng, Linzhao
    STEM CELLS TRANSLATIONAL MEDICINE, 2018, 7 (01) : 87 - 97