Preparation of cellulose nanofibril/titanium dioxide nanoparticle nanocomposites as fillers for PVA-based packaging and investigation into their intestinal toxicity

被引:30
作者
Yu, Zhilong [1 ]
Wang, Wei [1 ]
Sun, Lin [1 ]
Kong, Fanbin [2 ]
Lin, Mengshi [1 ]
Mustapha, Azlin [1 ]
机构
[1] Univ Missouri, Div Food Syst & Bioengn, Food Sci Program, Columbia, MO 65211 USA
[2] Univ Georgia, Dept Food Sci & Technol, Athens, GA 30602 USA
基金
美国食品与农业研究所;
关键词
Nanocellulose; Titanium dioxide nanoparticle; Food packaging; Intestinal bacteria; Human colon cell; Toxicity; TITANIUM-DIOXIDE; POLYVINYL-ALCOHOL; TIO2; NANOPARTICLES; FILMS; NANOCRYSTALS; TECHNOLOGIES; FABRICATION; MECHANISM;
D O I
10.1016/j.ijbiomac.2019.11.153
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The aims of this work were to synthesize cellulose nanofibril/titanium dioxide nanoparticle (CNF/TiO2NP) nanocomposites, evaluate the use of CNF/TiO2NP nanocomposites in PVA-based films, and investigate the intestinal toxicity of the nanocomposites. Via a mixing method, CNF/TiO2NP nanocomposites were synthesized. The addition of the nanocomposites significantly enhanced the tensile strength, Young's modulus, and light barrier capacity of PVA films. Moreover, a high concentration of CNF/TiO2NP nanocomposites (10 mg/mL) had no appreciable effect on the growth of Escherichia colt P-24, Lactobacillus acidophilus ADEL and Bifidobacterium animalis Bif-6 cells. The nanocomposites did not exhibit significant toxicity to cancerous and normal colon cells even when their concentrations increased to a high level of 1000 mu g/mL. The results indicate that CNF/TiO2NP nanocomposites can potentially be used as functional fillers for a PVA-based packaging system. (C) 2019 Elsevier B.V. All rights reserved.
引用
收藏
页码:1174 / 1182
页数:9
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