Hidden structure in protein energy landscapes

被引：4

作者：

Ming, Dengming ^{[1
,2
]}

Anghel, Marian ^{[1
]}

Wall, Michael E. ^{[1
,3
,4
]}

机构：

[1] Los Alamos Natl Lab, Comp Computat & Stat Sci Div, Los Alamos, NM 87545 USA

[2] Nanjing Univ, Sch Life Sci, Nanjing 210093, Jiangsu, Peoples R China

[3] Los Alamos Natl Lab, Biosci Div, Los Alamos, NM 87545 USA

[4] Los Alamos Natl Lab, Ctr Nonlinear Studies, Los Alamos, NM 87545 USA

来源：

PHYSICAL REVIEW E | 2008年 / 77卷 / 02期

关键词：

D O I：

10.1103/PhysRevE.77.021902

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

Inherent structure theory is used to discover strong connections between simple characteristics of protein structure and the energy landscape of a Go (o) over bar model. The potential energies and vibrational free energies of inherent structures are highly correlated, and both reflect simple measures of networks of native contacts. These connections have important consequences for models of protein dynamics and thermodynamics.

引用

页数：6

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