Potential Role of Akkermansia muciniphila in Parkinson's Disease and Other Neurological/Autoimmune Diseases

被引：18
|
作者：
Fang, Xin [1 ]
Li, Fang-jun [1 ]
Hong, Dao-jun [1 ]
机构：
[1] Nanchang Univ, Affiliated Hosp 1, Dept Neurol, Nanchang 330006, Jiangxi, Peoples R China
来源：
CURRENT MEDICAL SCIENCE | 2021年 / 41卷 / 06期
基金：
中国国家自然科学基金;
关键词：
Akkermansia muciniphila; gut microbiota; neurological diseases; Parkinson's disease; INSULIN-RESISTANCE; GUT MICROBIOTA; INFLAMMATION;
D O I：
10.1007/s11596-021-2464-5
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
The composition of the gut microbiota, including Akkermansia muciniphila (A. muciniphila), is altered in many neurological diseases and may be involved in the pathophysiological processes of Parkinson's disease (PD). A. muciniphila, a mucin-degrading bacterium, is a potential next-generation microbe that has anti-inflammatory properties and is responsible for keeping the body healthy. As the role of A. muciniphila in PD has become increasingly apparent, we discuss the potential link between A. muciniphila and various neurological diseases (including PD) in the current review.
引用
收藏
页码：1172 / 1177
页数：6
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