Facile Synthesis of 3-Amido-Dienynes via a Tandem -Propargylation-Isomerization of Chiral Allenamides and their Applications in Diels-Alder Cycloadditions

被引：2

作者：

Ma, Zhi-Xiong ^{[1
]}

Fang, Li-Chao

Haugen, Bryan J.

Bruckbauer, Daniel

Feltenberger, John B.

Hsung, Richard P. ^{[1
]}

机构：

[1] Univ Wisconsin, Sch Pharm, Div Pharmaceut Sci, Madison, WI 53705 USA

来源：

SYNLETT | 2017年 / 28卷 / 20期

关键词：

allenamide; tandem; 3-amido-dienyne; propargylation; Diels-Alder reaction; Pauson-Khand reaction; electrocyclization; RING CLOSURES; 2-AMIDO-DIENES;

D O I：

10.1055/s-0036-1590899

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of interesting 3-amido-dienynes was synthesized via tandem -propargylation-isomerization of chiral allenamides with moderate E/Z ratio. Reactivities of E and Z isomers were examined.

引用

页码：2906 / 2912

页数：7

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