Facile Synthesis of 3-Amido-Dienynes via a Tandem -Propargylation-Isomerization of Chiral Allenamides and their Applications in Diels-Alder Cycloadditions

被引：2
作者：
Ma, Zhi-Xiong [1 ]
Fang, Li-Chao
Haugen, Bryan J.
Bruckbauer, Daniel
Feltenberger, John B.
Hsung, Richard P. [1 ]
机构：
[1] Univ Wisconsin, Sch Pharm, Div Pharmaceut Sci, Madison, WI 53705 USA
来源：
SYNLETT | 2017年 / 28卷 / 20期
关键词：
allenamide; tandem; 3-amido-dienyne; propargylation; Diels-Alder reaction; Pauson-Khand reaction; electrocyclization; RING CLOSURES; 2-AMIDO-DIENES;
D O I：
10.1055/s-0036-1590899
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of interesting 3-amido-dienynes was synthesized via tandem -propargylation-isomerization of chiral allenamides with moderate E/Z ratio. Reactivities of E and Z isomers were examined.
引用
收藏
页码：2906 / 2912
页数：7
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