Anti-oxidant Effects of Kiwi Fruit in Vitro and in Vivo

被引:49
作者
Iwasawa, Haruyo [1 ]
Morita, Erika [2 ]
Yui, Satoru [2 ]
Yamazaki, Masatoshi [2 ]
机构
[1] Teikyo Univ, Fac Pharmaceut Sci, Ctr Educ Res, Itabashi Ku, Tokyo 1738605, Japan
[2] Teikyo Univ, Fac Pharmaceut Sci, Dept Med Life Chem, Midori Ku, Kanagawa 2525195, Japan
关键词
kiwi fruit; anti-oxidant effect; 8-hydroxy-2 '-deoxyguanosine; N-epsilon-(hexanoyl)-lysine; polyphenol; OXIDATIVE DNA-DAMAGE; PERILLA LEAF EXTRACT; ACTINIDIA-CHINENSIS; VITAMIN-C; GREEN TEA; KIWIFRUIT; STRESS; CONSUMPTION; CAPACITY; PLASMA;
D O I
10.1248/bpb.34.128
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
We previously reported that kiwi fruit is rich in polyphenols and has immunostimulatory activity. Polyphenols are widely known for having anti-oxidant effects. We also revealed potential anti-oxidant effects of kiwi fruit in vivo by oral administration to mice. Here, we compared the anti-oxidant effects of kiwi fruit with those of other fruits in vitro. Then, we examined the inhibitory effects of kiwi fruit on oxidation in the human body. There are two varieties of kiwi fruit, green kiwi and gold kiwi. We also examined variation between these varieties. Comparison of the anti-oxidant effects in vitro demonstrated that kiwi fruit had stronger anti-oxidant effects than orange and grapefruit, which are rich in vitamin C; gold kiwi had the strongest anti-oxidant effects. Kiwi fruit inhibited oxidation of biological substances in the human body. In particular, kiwi fruit may inhibit early lipid oxidation. In this study, kiwi fruit had strong anti-oxidant effects and may prevent the development and deterioration of diseases caused by oxidative stress.
引用
收藏
页码:128 / 134
页数:7
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