Design of photocleavable lipids and their application in liposomal "uncorking"

被引：32

作者：

Chandra, B ^{[1
]}

Mallik, S ^{[1
]}

Srivastava, DK ^{[1
]}

机构：

[1] N Dakota State Univ, Dept Chem Biochem & Mol Biol, Fargo, ND 58105 USA

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 24期

关键词：

D O I：

10.1039/b503423j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The design of o-nitrobenzyl containing photocleavable lipid-amino acid conjugates, and their application in liposomal uncorking are described.

引用

页码：3021 / 3023

页数：3

共 26 条

[1] Enzymatic release of antitumor ether lipids by specific phospholipase A2 activation of liposome-forming prodrugs [J].

Andresen, TL ;

Davidsen, J ;

Begtrup, M ;

Mouritsen, OG ;

Jorgensen, K .

JOURNAL OF MEDICINAL CHEMISTRY, 2004, 47 (07) :1694-1703

[2] Liposomes: Applications in medicine [J].

Banerjee, R .

JOURNAL OF BIOMATERIALS APPLICATIONS, 2001, 16 (01) :3-21

[3] Isotope effects in photochemistry.: 1.: o-Nitrobenzyl alcohol derivatives [J].

Blanc, A ;

Bochet, CG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (23) :7174-7175

[4] Bis(o-nitrophenyl)ethanediol:: A practical photolabile protecting group for ketones and aldehydes [J].

Blanc, A ;

Bochet, CG .

JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (03) :1138-1141

[5] Acid-triggered release from sterically stabilized fusogenic liposomes via a hydrolytic DePEGylation strategy [J].

Boomer, JA ;

Inerowicz, HD ;

Zhang, ZY ;

Bergstrand, N ;

Edwards, K ;

Kim, JM ;

Thompson, DH .

LANGMUIR, 2003, 19 (16) :6408-6415

[6] Secreted phospholipase A2 as a new enzymatic trigger mechanism for localised liposomal drug release and absorption in diseased tissue [J].

Davidsen, J ;

Jorgensen, K ;

Andresen, TL ;

Mouritsen, OG .

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2003, 1609 (01) :95-101

[7] Cholesterol phosphate derivatives: Synthesis and incorporation into a phosphatase and calcium-sensitive triggered release liposome [J].

Davis, SC ;

Szoka, FC .

BIOCONJUGATE CHEMISTRY, 1998, 9 (06) :783-792

[8] Liposomes for photodynamic therapy [J].

Derycke, ASL ;

de Witte, PAM .

ADVANCED DRUG DELIVERY REVIEWS, 2004, 56 (01) :17-30

[9] New functions for the matrix metalloproteinases in cancer progression [J].

Egeblad, M ;

Werb, Z .

NATURE REVIEWS CANCER, 2002, 2 (03) :161-174

[10] Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs [J].

Felnerova, D ;

Viret, JF ;

Glück, R ;

Moser, C .

CURRENT OPINION IN BIOTECHNOLOGY, 2004, 15 (06) :518-529

← 1 2 3 →