A novel, one-pot, three-component synthesis of 5H-[1,3]Thiazolo[3,2-a]pyrimidine derivatives

被引：12
作者：
Adib, Mehdi [1 ]
Nosrati, Meisam
Mahdavi, Mohammad
Zhu, Long-Guan
Mirzaei, Peiman
机构：
[1] Univ Tehran, Univ Coll Sci, Sch Chem, Tehran, Iran
[2] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China
[3] Shahid Beheshti Univ Med Sci, Dept Chem, Tehran, Iran
来源：
SYNLETT | 2007年 / 17期
关键词：
5H-[1,3]thiazolo[3,2-a]pyrimidines; three-component reaction; isocyanides; cyclizations; heterocycles;
D O I：
10.1055/s-2007-991048
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel synthesis of highly functionalized 5H-[1,3]thiazolo[3,2-a]pyrimidines is described via a one-pot, three-component addition reaction between isocyanides, dialkyl acetylenedicarboxylates and ethyl 2-oxo-2-(1,3-thiazol-2-ylainino)acetates in good yields.
引用
收藏
页码：2703 / 2706
页数：4
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