MUGEN mouse database; Animal models of human immunological diseases

被引：10

作者：

Aidinis, V. ^{[1
]}

Chandras, C. ^{[1
]}

Manoloukos, M. ^{[1
]}

Thanassopoulou, A. ^{[1
]}

Kranidioti, K. ^{[1
]}

Armaka, M. ^{[1
]}

Douni, E. ^{[1
]}

Kontoyiannis, D. L. ^{[1
]}

Zouberakis, M. ^{[1
]}

Kollias, G. ^{[1
]}

机构：

[1] BSRC Alexander Fleming, Vari 16672, Greece

来源：

NUCLEIC ACIDS RESEARCH | 2008年 / 36卷

关键词：

D O I：

10.1093/nar/gkm838

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The MUGEN mouse database (MMdb)(www.mugen-noe.org/database/) is a database of murine models of immune processes and immunological diseases. Its aim is to share and publicize information on mouse strain characteristics and availability from participating institutions. MMdbs basic classification of models is based on three major research application categories: Models of Human Disease, Models of Immune Processes and Transgenic Tools. Data on mutant strains includes detailed information on affected gene(s), mutant allele(s) and genetic background (DNA origin, gene targeted, host and backcross strain background). Each gene/transgene index also includes IDs and direct links to Ensembl, ArrayExpress, EURExpress and NCBIs Entrez Gene database. Phenotypic description is standardized and hierarchically structured, based on MGIs mammalian phenotypic ontology terms. Availability (e.g. live mice, cryopreserved embryos, sperm and ES cells) is clearly indicated, along with handling and genotyping details (in the form of documents or hyperlinks) and all relevant contact information (including EMMA and Jax/IMSR hyperlinks where available). MMdbs design offers a user-friendly query interface and provides instant access to the list of mutant strains and genes. Database access is free of charge and there are no registration requirements for data querying.

引用

页码：D1048 / D1054

页数：7

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