Geographic disparities in transplantation

被引:11
作者
Salvalaggio, Paolo R. [1 ]
机构
[1] Hosp Israelita Albert Einstein, Sao Paulo, Brazil
关键词
allocation; disparity; geography; transplantation; LIVER-TRANSPLANTATION; KIDNEY-TRANSPLANTATION; UNITED-STATES; ALLOCATION SYSTEM; LUNG TRANSPLANTATION; ORGAN ALLOCATION; IMPACT; ACCESS; WAITLIST; OUTCOMES;
D O I
10.1097/MOT.0000000000000914
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
Purpose of review The Final Rule clearly states that geography should not be a determinant of a chance of a potential candidate being transplanted. There have been multiple concerns about geographic disparities in patients in need of solid organ transplantation. Allocation policy adjustments have been designed to address these concerns, but there is little evidence that the disparities have been solved. The purpose of this review is to describe the main drivers of geographic disparities in solid organ transplantation and how allocation policy changes and other potential actions could impact these inequalities. Recent findings Geographical disparities have been reported in kidney, pancreas, liver, and lung transplantation. Organ Procurement and Transplant Network has modified organ allocation rules to underplay geography as a key determinant of a candidates' chance of receiving an organ. Thus, heart, lung, and more recently liver and Kidney Allocation Systems have incorporated broader organ sharing to reduce geographical disparities. Whether these policy adjustments will indeed eliminate geographical disparities are still unclear. Modern allocation policy focus in patients need, regardless of geography. Innovative actions to further reduce geographical disparities are needed.
引用
收藏
页码:547 / 553
页数:7
相关论文
共 75 条
[1]   Greater complexity and monitoring of the new Kidney Allocation System: Implications and unintended consequences of concentric circle kidney allocation on network complexity [J].
Adler, Joel T. ;
Husain, Syed A. ;
King, Kristen L. ;
Mohan, Sumit .
AMERICAN JOURNAL OF TRANSPLANTATION, 2021, 21 (06) :2007-2013
[2]   Changes in multiorgan heart transplants following the 2018 allocation policy change [J].
Afflu, Derek K. ;
Diaz-Castrillon, Carlos E. ;
Seese, Laura ;
Hess, Nicholas R. ;
Kilic, Arman .
JOURNAL OF CARDIAC SURGERY, 2021, 36 (04) :1249-1257
[3]  
[Anonymous], 1998, LANCET, V352, P79
[4]   Geographic variability in access to primary kidney transplantation in the United States, 1996-2005 [J].
Ashby, V. B. ;
Kalbfleisch, J. D. ;
Wolfe, R. A. ;
Lin, M. J. ;
Port, F. K. ;
Leichtman, A. B. .
AMERICAN JOURNAL OF TRANSPLANTATION, 2007, 7 (05) :1412-1423
[5]   Race and Receipt of Liver Transplantation: Location Matters [J].
Asrani, Sumeet K. ;
Kim, W. Ray ;
Kamath, Patrick S. .
LIVER TRANSPLANTATION, 2010, 16 (09) :1009-1012
[6]   The Evolution of Organ Allocation for Liver Transplantation Tackling Geographic Disparity Through Broader Sharing [J].
Axelrod, David A. ;
Vagefi, Parsia A. ;
Roberts, John P. .
ANNALS OF SURGERY, 2015, 262 (02) :224-227
[7]   Geographic disparities in donor lung supply and lung transplant waitlist outcomes: A cohort study [J].
Benvenuto, Luke J. ;
Anderson, David R. ;
Kim, Hanyoung P. ;
Hook, Jaime L. ;
Shah, Lori ;
Robbins, Hilary Y. ;
D'Ovidio, Frank ;
Bacchetta, Matthew ;
Sonett, Joshua R. ;
Arcasoy, Selim M. .
AMERICAN JOURNAL OF TRANSPLANTATION, 2018, 18 (06) :1471-1480
[8]   Use of Serum Sodium for Liver Transplant Graft Allocation: A Decade in the Making, Now Is It Ready for Primetime? [J].
Biggins, Scott W. .
LIVER TRANSPLANTATION, 2015, 21 (03) :279-281
[9]   Geographic Disparity in Deceased Donor Liver Transplant Rates Following Share 35 [J].
Bowring, Mary G. ;
Zhou, Sheng ;
Chow, Eric K. H. ;
Massie, Allan B. ;
Segev, Dorry L. ;
Gentry, Sommer E. .
TRANSPLANTATION, 2019, 103 (10) :2113-2120
[10]   Unfair Advantages for Hepatocellular Carcinoma Patients Listed for Liver Transplant in Short-Wait Regions Following 2015 Hepatocellular Carcinoma Policy Change [J].
Brondfield, Max N. ;
Dodge, Jennifer L. ;
Hirose, Ryutaro ;
Heimbach, Julie ;
Yao, Francis Y. ;
Mehta, Neil .
LIVER TRANSPLANTATION, 2020, 26 (05) :662-672