Baimantuoluosides D-G, Four New Withanolide Glucosides from the Flower of Datura metel L.

被引：44

作者：

Yang, Bing-you

Xia, Yong-gang

Wang, Qiu-hong

Dou, De-qiang ^{[2
]}

Kuang, Hai-xue ^{[1
]}

机构：

[1] Heilongjiang Univ Chinese Med, Coll Pharm, Harbin 150040, Peoples R China

[2] Liaoning Univ Tradit Chinese Med, Dalian 116600, Peoples R China

来源：

ARCHIVES OF PHARMACAL RESEARCH | 2010年 / 33卷 / 08期

基金：

中国国家自然科学基金;

关键词：

Datura metel L; Solananceae; Withanolide glucosides; Baimantuoluosides; CONSTITUENTS;

D O I：

10.1007/s12272-010-0802-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

In our search for bioactive anti-psoriasis compounds from the flower of Datura metel L, we isolated four new withanolide glucosides, baimantuoluosides D, E, F and G (1-4). The structures of the new compounds are (5 alpha,6 alpha,7 beta,22R)-5,6,7,27-tetrahydroxy-1-oxowitha-2,24-dien-27-O-beta-D-glucopyranoside (1), (5 alpha,6 beta,7 alpha,22R)-5,6,7,27-tetrahydroxy-1-oxowitha-2,24-dien-27-O-beta-D-glucopyranoside (2), (5 alpha,6 beta,7 alpha,12 beta,22R)-5,6,7,12,27-pentahydroxy-1-oxowitha-2,24-dien-27-O-beta-D-glucopyranoside (3), and (5 alpha,6 beta,22R)-5,6,27-trihydroxy-1-oxowitha-2,24-dien-27-O-beta-D-glucopyranoside (4) on the basis of chemical and physicochemical evidence.

引用

页码：1143 / 1148

页数：6

共 8 条

[1] CONSTITUENTS OF WITHANIA-SOMNIFERA DUN .13. WITHANOLIDES OF CHEMOTYPE-III [J].