A hybrid nanoparticle probe for dual-modality positron emission tomography and magnetic resonance imaging

被引:183
作者
Choi, Jin-sil [2 ]
Park, Jeong Chan [1 ]
Nah, Hyunsoo [2 ]
Woo, Seungtae [3 ]
Oh, Jieun [1 ]
Kim, Kyeong Min [5 ]
Cheon, Gi Jeong [2 ,5 ]
Chang, Yongmin [4 ]
Yoo, Jeongsoo [1 ]
Cheon, Jinwoo
机构
[1] Kyungpook Natl Univ, CMRI, Dept Mol Med & Nucl Med, Taegu 700422, South Korea
[2] Yonsei Univ, Dept Chem, Seoul 120749, South Korea
[3] Kyungpook Natl Univ, Dept Biomed Engn, Taegu 700422, South Korea
[4] Kyungpook Natl Univ, Dept Mol Med & Diagnost Radiol, Taegu 700422, South Korea
[5] Korea Inst Radiol & Med Sci, Mol Imaging Res Ctr, Seoul 139706, South Korea
关键词
imaging agents; magnetic resonance imaging; manganese; nanoparticles; positron emission tomography;
D O I
10.1002/anie.200801369
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Figure Presented) Creating a good image: A probe for combined positron emission tomography (PET) and magnetic resonance imaging (MRI) has high colloidal stability and demonstrates facile conjugation ability. Sentinel lymph nodes are clearly identified in the fusion image (see picture; I: injection site) because of the complementary nature of the techniques, which makes accurate anatomical information and fault-free diagnosis possible. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:6259 / 6262
页数:4
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