Synthesis and X-ray diffraction data of 6,8-dimethyl-cis-2-vinyl-2,3,4,5-tetrahydro-1H-benzo[b]azepin-4-ol and 8-chloro-9-methyl-cis-2-(prop-1-en-2-yl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-4-ol

被引：0
作者：
Macias, M. A. [1 ]
Henao, J. A. [1 ]
Maria Acosta, Lina [2 ]
Palma, Alirio [2 ]
机构：
[1] Univ Ind Santander, Fac Ciencias, Escuela Quim, Grp Invest Quim Estruct GIQUE, Bucaramanga 678, Colombia
[2] Univ Ind Santander, Fac Ciencias, Escuela Quim, Lab Sintesis Organ LSO,Ctr Invest Biomol,CIBIMOL, Bucaramanga 678, Colombia
来源：
POWDER DIFFRACTION | 2011年 / 26卷 / 04期
关键词：
tetrahydro-1-benzazepine; X-ray powder diffraction data; antiparasitic agents; TRYPANOSOMA-CRUZI; RELIABILITY; INHIBITORS; CRITERION; PAULLONES;
D O I：
10.1154/1.3656975
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
The 6,8-dimethyl-cis-2-vinyl-2,3,4,5-tetrahydro-1H-benzo[b]azepin-4-ol (2a) (Chemical formula C14H19NO) and 8-chloro-9-methyl-cis-2-(prop-1-en-2-yl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-4-ol (2b) (Chemical formula C14H18ClNO) were prepared via the reductive cleavage of the bridged N-O bond of the corresponding 1,4-epoxytetrahydro-1-benzazepines. The X-ray powder diffraction patterns for the new compounds were obtained. The compound 2a was found to crystallize in an orthorhombic system with space group Pmn2(1) (No. 31), refined unit-cell parameters a = 19.422(6) angstrom, b = 6.512(3) angstrom, c = 9.757(4) angstrom and V = 1234.0(5) angstrom(3). The compound 2b was found to crystallize in a monoclinic system with space group P2(1)/m (No. 11), refined unit-cell parameters a = 17.570(4) angstrom, b= 8.952(3) angstrom, c = 14.985(4) angstrom, beta = 101.66(2)degrees, and V = 2308.3(9) angstrom(3). (C) 2011 International Centre for Diffraction Data. [DOI: 10.1154/1.3656975]
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页码：346 / 349
页数：4
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