Combined pallidal and subthalamic nucleus stimulation in sporadic dystonia-parkinsonism Case report

被引:11
作者
Woehrle, Johannes C. [2 ]
Blahak, Christian [2 ]
Capelle, Hans-Holger [1 ]
Fogel, Wolfgang [3 ]
Baezner, Hansjoerg [2 ]
Krauss, Joachim K. [1 ]
机构
[1] Hannover Med Sch, Dept Neurosurg, MHH, D-30652 Hannover, Germany
[2] Univ Hosp Mannheim, Dept Neurol, Mannheim, Germany
[3] Stiftung Deutsch Klin Diagnost, Dept Neurol, Wiesbaden, Germany
关键词
pallidum; subthalamic nucleus; deep brain stimulation; dystonia-parkinsonism; functional neurosurgery; DEEP-BRAIN-STIMULATION; QUALITY-OF-LIFE; GLOBUS-PALLIDUS; SEGMENTAL DYSTONIA; CERVICAL DYSTONIA; TARDIVE DYSTONIA; FOLLOW-UP; DISEASE; INTERNUS; LUBAG;
D O I
10.3171/2011.8.JNS101552
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Multifocal deep brain stimulation (DBS) is a new technique that has been introduced recently. A 39-year-old man with dystonia-parkinsonism underwent the simultaneous implantation of subthalamic nucleus (STN) and globus pallidus internus (GPi) DBS electrodes. While bilateral STN DBS controlled the parkinsonian symptoms well and allowed for a reduction in levodopa, the improvement of dystonia was only temporary. Additional GPi DBS also alleviated dystonic symptoms. Formal assessment at the 1-year follow-up showed that both the parkinsonian symptoms and the dystonia were markedly improved via continuous bilateral combined STN and GPi stimulation. Sustained benefit was achieved at 3 years postoperatively. (DOI: 10.3171/2011.8.JNS101552)
引用
收藏
页码:95 / 98
页数:4
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