Bioactive phenolic compounds from a medicinal lichen, Usnea longissima

被引：63
作者：
Choudhary, MI [1 ]
Azizuddin [1 ]
Jalil, S [1 ]
Atta-ur-Rahman [1 ]
机构：
[1] Univ Karachi, HEJ Res Inst Chem, Int Ctr Chem Sci, Karachi 75270, Pakistan
来源：
PHYTOCHEMISTRY | 2005年 / 66卷 / 19期
关键词：
Usnea longissirna; lichen; Usneaceae; glutinol; longissiminone; anti-inflammatory; cytotoxicity;
D O I：
10.1016/j.phytochem.2005.06.023
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Natural products, longissiminone A (1) and longissiminone B (2), were isolated along with a known compound, glutinol (3), from a medicinal lichen, Usnea longissima. The structures of compounds 1 and 2 were determined with the help of spectroscopic studies. Compound 1 was found to possess potent anti-inflammatory activity in a cell-based contemporary assay. Cytotoxicity activity measured by cell viability assay showed 100% viability in the presence of 200 mu g/mL cone. of these compounds. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2346 / 2350
页数：5
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